Ingestible Bio-Electronic Device Could Monitor GI Health

Share this content:
Ingestible Bio-Electronic Device Could Monitor GI Health
Ingestible Bio-Electronic Device Could Monitor GI Health

THURSDAY, May 24, 2018 (HealthDay News) -- An ingestible micro-bio-electronic device (IMBED) could be used for in situ biomolecular detection based on environmentally resilient biosensor bacteria and luminescence readout electronics, according to a study published in the May 25 issue of Science.

Noting that biomolecular monitoring in the gastrointestinal tract could offer rapid, precise disease detection and management, Mark Mimee, from the Massachusetts Institute of Technology in Cambridge, and colleagues presented an IMBED for biomolecular detection in situ. The device was based on environmentally resilient biosensor bacteria and miniaturized luminescence readout electronics that communicate with an external device wirelessly.

The researchers engineered heme-sensitive probiotic biosensors as proof of concept. In swine, these demonstrated accurate diagnosis of gastrointestinal bleeding. To demonstrate modulatory and extensibility of the detection platform, alternative biosensors were integrated.

"IMBEDs enable new opportunities for gastrointestinal biomarker discovery and could transform the management and diagnosis of gastrointestinal disease," the authors write.

Two authors have filed a patent application based on the microbial heme sensor and/or the integrated device.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Both Abstinence and High Alcohol Use Linked to Dementia

Both Abstinence and High Alcohol Use Linked to ...

Increased dementia risk for those with abstinence or with drinking >14 units alcohol/week in midlife

Intervention Cuts Risk for HIV in Young Transgender Women

Intervention Cuts Risk for HIV in Young Transgender ...

Intervention group had greater reduction in condomless sex acts versus standard of care group

Trauma Surgery Association IDs Steps to Curb Firearm Violence

Trauma Surgery Association IDs Steps to Curb Firearm ...

14 recommendations include actions to be taken by federal government, professional bodies

is free, fast, and customized just for you!




Already a member?

Sign In Now »