Immunotherapy Promising for Tx of Acute Myeloid Leukemia

Share this content:
Immunotherapy Promising for Tx of Acute Myeloid Leukemia
Immunotherapy Promising for Tx of Acute Myeloid Leukemia

THURSDAY, Sept. 22, 2016 (HealthDay News) -- A new type of immunotherapy involving natural killer (NK) cells may help treat acute myeloid leukemia (AML) patients, according to a study published in the Sept. 21 issue of Science Translational Medicine.

Todd Fehniger, M.D., Ph.D., associate professor of medicine at Washington University in St. Louis, and colleagues sought to enhance the inherent capabilities of NK cells. The researchers started with NK cells donated by patients' close relatives. Those cells were incubated overnight in a mixture of interleukins 12, 15, and 18.

Of nine AML patients who were given the therapy and could be followed, four had a complete remission for up to six months. A fifth had a partial remission. There were no major safety problems, according to Fehniger. Patients had only mild side effects, such as a slight fever.

The next step, Fehniger told HealthDay, is to test the NK therapy in a larger number of patients, at the highest dose used in this initial study. The researchers also plan to study NK cells in combination with other therapies, including "mini" bone marrow transplants.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Phone-Based Intervention Aids Rheumatoid Arthritis Care

Phone-Based Intervention Aids Rheumatoid Arthritis Care

Educational phone calls with nurses promote shared decision making in care

Early PT Linked to Less Opioid Use in Musculoskeletal Pain

Early PT Linked to Less Opioid Use in ...

For opioid-naive patients, early physical therapy tied to less opioid use in shoulder, neck, knee, back pain

Emotional Stress of Holidays Can Trigger Heart Attacks

Emotional Stress of Holidays Can Trigger Heart Attacks

Higher risk seen on Christmas Eve, particularly in older adults with diabetes, heart disease

is free, fast, and customized just for you!




Already a member?

Sign In Now »