Higher Vitamin D Levels May Lower Breast Cancer Risk

Share this content:
Higher Vitamin D Levels May Lower Breast Cancer Risk
Higher Vitamin D Levels May Lower Breast Cancer Risk

FRIDAY, July 13, 2018 (HealthDay News) -- Higher levels of vitamin D may be protective against breast cancer, according to a study published online June 15 in PLOS ONE.

Sharon L. McDonnell, M.P.H., from GrassrootsHealth in Encinitas, Calif., and colleagues examined the relationship between 25-hydroxyvitamin D (25[OH]D concentration and breast cancer risk across a broad range of 25(OH)D concentrations (<20 to ≥60 ng/mL) among women aged 55 years and older participating in three previous studies (pooled cohort, 5,038 participants).

The researchers found that 77 women were diagnosed with breast cancer (age-adjusted incidence: 512 cases per 100,000 person-years). There was an 82 percent lower incidence rate of breast cancer for women with 25(OH)D concentrations ≥60 versus <20 ng/mL (rate ratio [RR], 0.18; P = 0.006). Kaplan-Meier curves for concentrations of <20, 20 to 39, 40 to 59, and ≥60 ng/mL were significantly different, with the highest proportion of breast cancer-free participants in the ≥60 ng/mL group (99.3 percent) and the lowest proportion of breast cancer-free participants in the <20 ng/mL group (96.8 percent) (P = 0.02). When adjusting for age, body mass index, smoking status, calcium supplement intake, and study of origin, women with 25(OH)D concentrations ≥60 ng/mL had an 80 percent lower risk of breast cancer than women with concentrations <20 ng/mL (hazard ratio, 0.20; P = 0.03).

"Higher 25(OH)D concentrations were associated with a dose-response decrease in breast cancer risk, with concentrations ≥60 ng/mL being most protective," the authors write.

Bio-Tech Pharmacal, Pure North S'Energy Foundation, and the Vitamin D Society funded the study.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Approves First Customizable Insulin Pump

FDA Approves First Customizable Insulin Pump

Product works by delivering insulin under the skin at set or variable rates

Sepsis Common in Terminal Hospitalizations, Discharges

Sepsis Common in Terminal Hospitalizations, Discharges

Most common underlying causes of death in sepsis are solid and hematologic cancers, chronic heart disease

Fewer Older Men Assessed, Treated for Osteoporosis

Fewer Older Men Assessed, Treated for Osteoporosis

Fewer older men than women, even with higher risk, undergo DXA screening, 25(OH)D measurement

is free, fast, and customized just for you!




Already a member?

Sign In Now »