Higher Incidence of Paradoxical Adipose Hyperplasia Reported

This article originally appeared here.
Share this content:
Higher Incidence of Paradoxical Adipose Hyperplasia Reported
Higher Incidence of Paradoxical Adipose Hyperplasia Reported

(HealthDay News) -- The incidence of paradoxical adipose hyperplasia (PAH) following cryolipolysis may be higher than previously described, according to a report published in the August issue of Lasers in Surgery and Medicine.

Noting that the incidence of PAH has been estimated at 0.0051 percent, Selina M. Singh, M.D., from the University of Texas Health Science Center in Houston, and colleagues describe two cases of PAH from a single practice. The two men underwent cryolipolysis treatments, and had demarcated tissue growth in the treatment areas after treatment. Both men underwent corrective liposuction treatment. Adipose tissue samples were collected from the treated and non-treated areas, and were processed and stained.

The researchers found that the incidence of PAH within a single practice was 0.47 percent; two in 422 cryolipolysis treatments. An increased number of adipocytes, fibrosis, and scar tissue were seen on histopathologic examination of the subcutaneous tissue mass in the treated areas compared with control areas. On histopathologic examination of the affected tissues no lipoblasts were identified.

"By understanding the pathogenesis, this rare adverse effect may be avoided, or even utilized as a therapeutic alternative for the treatment of congenital or acquired lipodystrophy," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »