High CVD Risk in Patients With Head, Neck Squamous Cell Cancer

Share this content:
High CVD Risk in Patients With Head, Neck Squamous Cell Cancer
High CVD Risk in Patients With Head, Neck Squamous Cell Cancer

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Twenty-three percent of patients with head and neck squamous cell carcinoma (HNSCC) have cardiovascular disease (CVD) at diagnosis, and 24 percent have uncontrolled blood pressure, according to research published online Dec. 29 in Head & Neck.

Christian C. Okoye, M.D., from Case Western Reserve University in Cleveland, and colleagues retrospectively reviewed patients with HNSCC who underwent definitive or adjuvant (chemo)radiation between 2011 and 2013. The authors calculated the 10-year risk estimates for a cardiovascular disease event according to the Framingham Risk Score (FRS).

One hundred fifteen patients with mainly stage III/IV HNSCC were followed up for a median of two years. The researchers found that 23 percent of patients had CVD at diagnosis. Patients with laryngeal cancer had higher FRS than those with cancer at other sites (20.5 versus 14.4 percent). At diagnosis, 24 percent of all patients had uncontrolled blood pressure. Forty-one and 30 percent of patients with CVD were not taking antiplatelet therapy or statin therapy, respectively. Indications for initiating statin therapy were seen for 34 percent of patients with CVD.

"Patients with HNSCC have a high baseline CVD risk and many do not receive optimal preventive care," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »