HCV-Infected Kidney Transplant More Efficient in HCV-Infected

Share this content:
HCV-Infected Kidney Transplant More Efficient in HCV-Infected
HCV-Infected Kidney Transplant More Efficient in HCV-Infected

TUESDAY, July 10, 2018 (HealthDay News) -- For patients with hepatitis C virus (HCV) infection with end-stage renal disease, transplant of an HCV-infected kidney followed by treatment is more cost-effective than transplant of an HCV-uninfected kidney, according to a study published online July 10 in the Annals of Internal Medicine.

Mark H. Eckman, M.D., from the University of Cincinnati, and colleagues compared the cost-effectiveness of transplanting HCV-infected or HCV-uninfected kidneys into HCV-infected patients. Transplant of an HCV-infected kidney was followed by HCV treatment, while transplant of an uninfected kidney was preceded by treatment.

The researchers found that, compared with transplant of an uninfected kidney, preceded by treatment, transplant of an HCV-infected kidney, followed by HCV treatment, was more effective and less costly in base-case analysis; this was mainly due to longer wait times for uninfected kidneys. An average of 0.5 quality-adjusted life-years would be gained at a lifetime cost savings of $41,591 for a typical 57.8-year-old patient receiving hemodialysis. In sensitivity analysis, transplant of an HCV-infected kidney continued to be preferred. Unless the additional wait time for an uninfected kidney was less than 161 days, transplant of an HCV-uninfected kidney preceded by HCV treatment was not preferred.

"Transplanting HCV-infected kidneys into HCV-infected patients increased quality-adjusted life expectancy and reduced costs compared with transplanting HCV-uninfected kidneys into HCV-infected patients," the authors write.

The study was funded by a grant from Merck Sharp & Dohme.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Increase Seen in Salmonella Illnesses From Ground Beef

CDC: Increase Seen in <i>Salmonella</i> Illnesses From Ground ...

246 people now sickened; 59 people have been hospitalized; no deaths reported to date

Epinephrine Personal Autoinjectors Cost-Effective at 24

Epinephrine Personal Autoinjectors Cost-Effective at &#36;24

Based on 10-fold fatality risk difference, value-based price for personal epinephrine $24

Burden of Liver Cancer Rising in Medicare Patients

Burden of Liver Cancer Rising in Medicare Patients

Coexistence of other liver conditions tied to even higher risk for death, health care costs

is free, fast, and customized just for you!




Already a member?

Sign In Now »