FDA Approves Avelox for Treatment of Plague

Share this content:
FDA Approves Avelox for Treatment of Plague
FDA Approves Avelox for Treatment of Plague

(HealthDay News) -- Avelox (moxifloxacin) was approved by the U.S. Food and Drug Administration on Friday to treat plague, a rare but deadly bacterial infection that can strike the lungs (pneumonic), blood (septicemic), or lymph nodes (bubonic).

Only 1,000 to 2,000 cases are reported worldwide annually, the agency said in a news release. It's spread by the bites of infected fleas, or by contact with infected animals or people. However, the Yersinia pestis bacterium could be released intentionally as a bioterrorism agent.

Avelox was approved under rules that allow findings from well-controlled animal studies (in this case, African green monkeys) in instances when it isn't ethical or feasible to conduct trials among humans. The disease is so rare that it wouldn't be possible to conduct adequate trials involving people, the FDA said.

Avelox's label carries a boxed warning of the potential for tendinitis and tendon rupture, and worsening muscle weakness among certain prone users. Other potential side effects include allergic reaction, liver damage, blood abnormalities, abnormal heart rhythm, and central nervous system problems.

Avelox is produced by Bayer Healthcare Pharmaceuticals, based Whippany, N.J.

More Information

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Bayer Stops U.S. Sale of Essure Birth Control Implant

Bayer Stops U.S. Sale of Essure Birth Control ...

Problems with device include chronic pain and perforations of the uterus and fallopian tubes

C.S. Mott Poll Addresses Child Safety at Amusement Parks

C.S. Mott Poll Addresses Child Safety at Amusement ...

2016 saw U.S. emergency departments deal with 30,000 injuries linked to amusement parks, carnivals

Greening Vacant Land Improves Neighborhood Mental Health

Greening Vacant Land Improves Neighborhood Mental Health

Cleaning up vacant lots in resource-limited urban settings can aid residents' mental health

is free, fast, and customized just for you!




Already a member?

Sign In Now »