Even Light-Use Waterpipe Smoking Harms the Lungs

Share this content:
Even Light-Use Waterpipe Smoking Harms the Lungs
Even Light-Use Waterpipe Smoking Harms the Lungs

FRIDAY, April 1, 2016 (HealthDay News) -- Young, light-use waterpipe smokers exhibit a variety of pulmonary abnormalities, according to a study published online March 23 in the American Journal of Respiratory and Critical Care Medicine.

Yael Strulovici-Barel, M.D., from the Weill Cornell Medical College in New York City, and colleagues compared clinical and biological parameters in young, light-use waterpipe-only smokers versus lifelong nonsmokers. Measured parameters included cough and sputum scores, lung function, chest high resolution computed tomography, lung epithelial lining fluid (ELF) metabolome, small airway epithelial (SAE) cell differential and transcriptome, alveolar macrophage (AM) transcriptome, and plasma apoptotic endothelial cell microparticles (EMPs).

Compared to nonsmokers, the researchers found that waterpipe smokers had more cough and sputum. Waterpipe smokers also exhibited lower lung diffusing capacity, abnormal ELF metabolome profile, increased proportions of SAE secretory and intermediate cells, reduced proportions of SAE ciliated and basal cells, markedly abnormal SAE and AM transcriptomes, and elevated levels of apoptotic EMPs, compared to nonsmokers.

"Young, light-use waterpipe-only smokers have a variety of abnormalities in multiple lung-related biologic and clinical parameters, suggesting that even limited waterpipe use has broad consequences on human lung biology and health," the authors write. "We suggest that large epidemiologic studies should be initiated on the harmful effects of waterpipe smoking."

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »