Erlotinib Overdose Tied to Conjunctivitis

This article originally appeared here.
Share this content:
Erlotinib Overdose Tied to Conjunctivitis
Erlotinib Overdose Tied to Conjunctivitis

FRIDAY, Nov. 17, 2017 (HealthDay News) -- Overdosing of erlotinib may be associated with rapid onset of conjunctivitis, according to a case report published online Oct. 25 in the Journal of Clinical Pharmacy and Therapeutics.

P. Sun, from the First Affiliated Hospital of Sun Yat-sen University in Guangzhou, China, and colleagues describe the case of a 72-year-old male with metastatic non-small-cell lung cancer who developed conjunctivitis after accidentally taking erlotinib at a dosage of 300 mg/day for four days.

The authors report that the patient had been taking erlotinib at the prescribed dose of 150 mg/day for 17 days. The conjunctivitis was successfully treated symptomatically while erlotinib was discontinued for seven days. The adverse effect did not recur when the patient resumed taking erlotinib 150 mg/day, suggesting the ocular change was related to the overdosing of erlotinib.

"Awareness and close monitoring of this adverse effect are helpful for doctors and pharmacists to identify inadvertent drug overdose," the authors write. "Patients should be provided comprehensive education before receiving targeted therapy."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Ground Beef Recalled After E. Coli Outbreak

Ground Beef Recalled After <i>E. Coli</i> Outbreak

Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.

Prevalence of Alzheimer's, Related Dementia Set to Double

Prevalence of Alzheimer's, Related Dementia Set to Double

Alzheimer's disease and related dementias burden is expected to increase to 3.3 percent in 2060

Long-Term Outcomes of Breast Implants Explored

Long-Term Outcomes of Breast Implants Explored

Higher rates of Sjogren syndrome, scleroderma, RA, stillbirth, melanoma for silicone implants

is free, fast, and customized just for you!




Already a member?

Sign In Now »