Epinephrine Personal Autoinjectors Cost-Effective at $24

Share this content:
Epinephrine Personal Autoinjectors Cost-Effective at $24
Epinephrine Personal Autoinjectors Cost-Effective at $24

FRIDAY, Nov. 16, 2018 (HealthDay News) -- In a simulation of children with peanut allergy, epinephrine personal autoinjectors are cost-effective at $24, according to a study published online Nov. 16 in JAMA Network Open.

Marcus Shaker, M.D., from the Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire, and Matthew Greenhawt, M.D., from the University of Colorado School of Medicine in Aurora, assessed cost ceilings for value-based epinephrine prices in peanut allergy. They compared a cohort of children with a peanut allergy who had been prescribed epinephrine autoinjectors to children with a peanut allergy not receiving personal epinephrine prescriptions.

A total of 100,000 simulated infants with peanut allergy entered each strategy; two-thirds of the group received annual personal epinephrine prescriptions and used these devices appropriately. The researchers found that the cost of anaphylaxis preparedness and treatment was $25,478 in those with personal epinephrine devices versus $654 in those without personal epinephrine. The average food allergy fatality was 0.00056 and 0.00148 per patient prescribed self-injectable epinephrine and not prescribed self-injectable epinephrine, respectively. Based on a 10-fold fatality risk difference, the value-based price for personal epinephrine was $24. The autoinjector incremental cost-effectiveness ratio was $2,742,697 per quality-adjusted life-year at a market cost of $715 per twin pack. The value-based price ceiling for a personal autoinjector was $264 if a hypothetical fatality risk protection from personal epinephrine was modeled at 100-fold.

"Current autoinjector prices are not cost-effective in preventing an outcome of fatality from food allergy," the authors write.

Several authors disclosed financial ties to the biopharmaceutical industry.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »