Enlarged Kidneys in Neonates With Congenital Heart Disease

Share this content:
Enlarged Kidneys in Neonates With Congenital Heart Disease
Enlarged Kidneys in Neonates With Congenital Heart Disease

WEDNESDAY, Sept. 26, 2018 (HealthDay News) -- Neonates with congenital heart disease (CHD) have enlarged kidneys on average, according to a study published online Sept. 11 in Pediatric Research.

Noting that as part of the "brain-sparing phenomenon," blood flow is redirected toward the growing brain in fetuses with CHD, which may result in impaired fetal growth, Gemma B. Scholes, from the University of Melbourne in Australia, and colleagues examined kidney growth using preoperative ultrasound measurements of kidney length from 452 neonates requiring surgery for CHD.

The researchers found that neonates with CHD had significantly enlarged kidneys as a cohort; depending on which of three normal population datasets was used for comparison, the mean percentile ranged from 54.1 to 72.7. Neonates with left heart obstruction consistently had kidneys that were greater than normal; in contrast, those with cyanotic heart disease had normal or enlarged kidneys depending on the reference population used.

"The kidneys of newborns with CHD are not reduced in size, and on average are larger than normal," the authors write. "The nature of this size discrepancy and its subsequent clinical significance is unknown."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »