Early Transfusion Tied to Lower Mortality in Combat Casualties

Share this content:
Early Transfusion Tied to Lower Mortality in Combat Casualties
Early Transfusion Tied to Lower Mortality in Combat Casualties

WEDNESDAY, Oct. 25, 2017 (HealthDay News) -- Blood product transfusion pre-hospital or within minutes of injury is associated with improved survival among medically evacuated U.S. military combat casualties in Afghanistan, according to a study published online Oct. 24 in the Journal of the American Medical Association.

Stacy A. Shackelford, M.D., from Fort Sam Houston in San Antonio, Texas, and colleagues examined the correlation of pre-hospital transfusion and time to initial transfusion with injury survival in a retrospective cohort study involving U.S. military combat casualties in Afghanistan. Data were included for 502 patients.

The researchers found that 5 percent of 55 pre-hospital transfusion recipients and 19 percent of 447 nonrecipients died within 24 hours of medical evacuation (MEDEVAC) rescue (between-group difference, −14 percent). By day 30, 11 and 23 percent had died (between-group difference, −12 percent). The adjusted hazard ratio for mortality associated with pre-hospital transfusion was 0.26 and 0.39 over 24 hours and 30 days, respectively. There were correlations for time to initial transfusion, regardless of location, with reduced 24-hour mortality only up to 15 minutes after MEDEVAC rescue (median, 36 minutes after injury: adjusted hazard ratio, 0.17).

"Among medically evacuated U.S. military combat causalities in Afghanistan, blood product transfusion pre-hospital or within minutes of injury was associated with greater 24-hour and 30-day survival than delayed transfusion or no transfusion," the authors write. "The findings support pre-hospital transfusion in this setting."

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

High Uptake, Acceptability of Rapid Fentanyl Test Strips

High Uptake, Acceptability of Rapid Fentanyl Test Strips

Significant link between receiving positive results, reporting positive change in overdose risk behavior

ACR: Walking Each Day May Cut Risk for TKA Over Five Years

ACR: Walking Each Day May Cut Risk for ...

Replacing 5 minutes of non-walking time with 5 minutes of moderate-to-vigorous walking beneficial

Short Respiratory Event Duration Ups Mortality Risk in OSA

Short Respiratory Event Duration Ups Mortality Risk in ...

Individuals with shortest-duration events had adjusted hazard ratio of 1.31 for all-cause mortality

is free, fast, and customized just for you!




Already a member?

Sign In Now »