December 2014 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for December 2014. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Novel Mutation in Leptin Gene Tied to Early-Onset Obesity

WEDNESDAY, Dec. 31, 2014 (HealthDay News) -- A mutation in the gene encoding leptin (LEP) resulting in biologically inactive leptin can cause early-onset extreme obesity, according to a brief report published in the Jan. 1 issue of the New England Journal of Medicine.

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AMA Identifies Top 10 Issues That Affected Docs in 2014

WEDNESDAY, Dec. 31, 2014 (HealthDay News) -- The top 10 issues that affected physicians in 2014 include many regulatory issues relating to Medicare and data release, as well as health issues such as overprescribing of antibiotics and the Ebola crisis, according to a report published by the American Medical Association (AMA).

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Ebola, ACA, VA Scandal Top U.S. Health News for 2014

WEDNESDAY, Dec. 31, 2014 (HealthDay News) -- It started as a deadly but little-known outbreak in West Africa, but the lethal and unchecked spread of the Ebola virus dominated U.S. headlines for much of 2014, making it one of the year's top health news features.

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Surgeon General Still Has Important Role to Play

TUESDAY, Dec. 30, 2014 (HealthDay News) -- The Surgeon General has an important role in educating and mobilizing the public and shaping policy on public health issues, according to an ideas and opinions piece published online Dec. 30 in the Annals of Internal Medicine.

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Both Sexes Fight the Same Battle to Lose Weight

TUESDAY, Dec. 30, 2014 (HealthDay News) -- Current evidence does not show any difference between men and women with regard to which strategies are most effective in achieving weight loss, according to research published online Dec. 11 in Obesity Reviews.

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Adverse Outcomes With Unmet Material Needs in Diabetes

MONDAY, Dec. 29, 2014 (HealthDay News) -- For adults with diabetes mellitus, unmet material needs are associated with poor diabetes control and increased health care resource use, according to a study published online Dec. 29 in JAMA Internal Medicine.

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Physical Activity Assessment Indicates Cardiometabolic Risk

MONDAY, Dec. 29, 2014 (HealthDay News) -- Physical activity, as assessed by the Exercise Vital Sign (EVS), is associated with improved cardiometabolic profile, according to research published Dec. 18 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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FDA Approves Saxenda for Weight Management

MONDAY, Dec. 29, 2014 (HealthDay News) -- Saxenda (liraglutide [rDNA origin] injection) has been approved by the U.S. Food and Drug Administration as a treatment option for chronic weight management, along with a reduced-calorie diet and physical activity.

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2015 Medicare Fee Schedule Offers Payment for Chronic Care

WEDNESDAY, Dec. 24, 2014 (HealthDay News) -- The 2015 Medicare Fee Schedule includes a Current Procedural Terminology Code that pays for clinical staff time for developing and implementing a care plan for patients with two or more chronic conditions, according to an article published Dec. 18 in Medical Economics.

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ADA Issues New Standards of Medical Care for Diabetes

WEDNESDAY, Dec. 24, 2014 (HealthDay News) -- New standards of care have been issued by the American Diabetes Association (ADA) and published as a supplement to the January issue of Diabetes Care.

Standards of Medical Care in Diabetes-2015

Metformin Seems Safe for Some With Impaired Kidney Function

TUESDAY, Dec. 23, 2014 (HealthDay News) -- For individuals with impaired kidney function, evidence suggests that metformin use is safe in those with mild or moderate disease, according to a review published in the Dec. 24/31 issue of the Journal of the American Medical Association.

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Review: Managing Celiac Disease in T1DM Patients

TUESDAY, Dec. 23, 2014 (HealthDay News) -- More research is needed to fully understand the correlation between celiac disease and type 1 diabetes, as well as the effects of a gluten-free diet, according to a review published in the January issue of Diabetes, Obesity and Metabolism.

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Asian-Americans to Be Screened for T2DM at Lower BMI

TUESDAY, Dec. 23, 2014 (HealthDay News) -- The American Diabetes Association (ADA) has lowered the body mass index (BMI) at which Asian-Americans should be screened for type 2 diabetes.

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Resistance Training Key for Men Fighting Age-Related Weight Gain

TUESDAY, Dec. 23, 2014 (HealthDay News) -- For men, combining aerobic activities with weight training is key to preserving muscle and avoiding weight gain, particularly age-related increases in waist circumference, according to research published online Dec. 22 in Obesity.

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HbA1c <7.6% Cuts Long-Term Vascular Complications in T1DM

MONDAY, Dec. 22, 2014 (HealthDay News) -- For patients with type 1 diabetes, long-term weighted mean hemoglobin A1c (HbA1c) is associated with development of severe microvascular complications, according to a study published online Dec. 15 in Diabetes Care.

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Thiazide Prophylaxis for Kidney Stones Doesn't Increase DM Risk

MONDAY, Dec. 22, 2014 (HealthDay News) -- The risk of diabetes mellitus is not increased with thiazide diuretic prophylaxis for kidney stones, according to research published in the December issue of The Journal of Urology.

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Tips Offered to Docs, Spouses for Maintaining Happy Marriage

FRIDAY, Dec. 19, 2014 (HealthDay News) -- Simple tips can help physicians and their spouses maintain marital happiness, according to an article published in the American Medical Association (AMA) Alliance magazine Physician Family.

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Study Explores Effects of Metformin in Obese Children

THURSDAY, Dec. 18, 2014 (HealthDay News) -- For obese hyperinsulinemic children, metformin seems to decrease perceived hunger and increase perceived fullness, according to a study published online Dec. 8 in Diabetes, Obesity and Metabolism.

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Low-Glycemic Index Diet Does Not Improve CV Risk Factors

WEDNESDAY, Dec. 17, 2014 (HealthDay News) -- Low-glycemic index (GI) diets may not improve cardiovascular risk factors such as insulin sensitivity, lipid levels, and systolic blood pressure, according to research reported in the Dec. 17 issue of the Journal of the American Medical Association.

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Digital Self-Scheduling Set to Increase Considerably by 2019

WEDNESDAY, Dec. 17, 2014 (HealthDay News) -- Digital self-scheduling is set to increase considerably in the next five years, according to a report published by Accenture.

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Hypoglycemia Ups Cardio Events, Mortality for Insulin-Treated

WEDNESDAY, Dec. 17, 2014 (HealthDay News) -- For insulin-treated patients with type 1 and type 2 diabetes, hypoglycemia is associated with increased risk of cardiovascular events and all-cause mortality, according to a study published online Dec. 9 in Diabetes Care.

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Challenges ID'd in Development of the Physician Compare Website

TUESDAY, Dec. 16, 2014 (HealthDay News) -- Under the Affordable Care Act (ACA), information must be made available to allow the public to compare physicians, although there are considerable challenges surrounding the development of the physician performance website, Physician Compare. These challenges are addressed in a health policy brief published online Dec. 11 in Health Affairs.

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Support for Electronic Health Information Varies With Use

TUESDAY, Dec. 16, 2014 (HealthDay News) -- Consent and purpose are important for public support of secondary uses of electronic health information, according to a study published in the Dec. 16 issue of the Annals of Internal Medicine.

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Physicians Reminded of Ethical Obligations Regarding Torture

TUESDAY, Dec. 16, 2014 (HealthDay News) -- With the issuing of the new U.S. Senate report on interrogations, the American Medical Association (AMA) is reminding physicians of their ethical obligations relating to torture and interrogation.

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Physicians Should Scrutinize Job Offers Before Accepting

MONDAY, Dec. 15, 2014 (HealthDay News) -- Physicians should scrutinize job offers and pay attention to specific issues before accepting a job, according to an article published Dec. 3 in Medical Economics.

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Webcast Scheduled to Discuss Maintenance of Certification

MONDAY, Dec. 15, 2014 (HealthDay News) -- New data relating to Maintenance of Certification (MOC) will be discussed in a free webcast to be held Dec. 17 by the Journal of the American Medical Association (JAMA).

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Fiber Fermentation By-Product May Help Prevent Weight Gain

MONDAY, Dec. 15, 2014 (HealthDay News) -- Propionate, a fatty acid created when fiber ferments in the colon, appears to prevent weight gain and trim fat around the waist, according to research published online Dec. 10 in Gut. However, the chemical compound doesn't seem to help people lose pounds, and the preliminary study is so small that the findings could be misleading.

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Tips Offered for Docs to Manage Their Online Reputation

FRIDAY, Dec. 12, 2014 (HealthDay News) -- Physicians can manage their online reputation, according to a report from the American Medical Association (AMA).

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Thyroidectomy, Statins May Cut Risk of Graves Ophthalmopathy

FRIDAY, Dec. 12, 2014 (HealthDay News) -- Both thyroidectomy and statin use are associated with lower risk of developing thyroid-associated ophthalmopathy (TAO) in individuals with Graves disease (GD), according to research published online Dec. 11 in JAMA Ophthalmology.

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Increased Insulin Resistance in Rheumatoid Arthritis

THURSDAY, Dec. 11, 2014 (HealthDay News) -- Patients with rheumatoid arthritis (RA) have elevated insulin resistance (IR), but this is not associated with increased atherosclerosis risk, according to a study published online Dec. 10 in Arthritis & Rheumatology.

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Dietary Intake Tool Validated for Renal Patients With Low Literacy

THURSDAY, Dec. 11, 2014 (HealthDay News) -- A renal food frequency questionnaire (RFF) is a valid and reliable tool for patients with limited literacy, according to a study published online Dec. 6 in the Journal of Renal Care.

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Autologous Islet Transplant With Remote Islet Isolation Safe

THURSDAY, Dec. 11, 2014 (HealthDay News) -- Autologous islet transplantation with remote islet isolation after pancreas resection seems safe and effective for chronic pancreatitis, according to a study published online Dec. 10 in JAMA Surgery.

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Adverse Outcomes Up With Elevated HbA1c in Late Pregnancy

THURSDAY, Dec. 11, 2014 (HealthDay News) -- Elevated hemoglobin A1c (HbA1c) during the second and third trimesters correlates with increased risk of adverse pregnancy outcomes, according to a study published online Nov. 3 in Diabetes Care.

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More Students Enrolling in U.S. Medical Schools

WEDNESDAY, Dec. 10, 2014 (HealthDay News) -- More students are enrolling in medical schools, and enrollees are more diverse than before, according to a report from the Association of American Medical Colleges (AAMC) published by the American Medical Association (AMA).

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More Docs, Patients Not Speaking Same Language

WEDNESDAY, Dec. 10, 2014 (HealthDay News) -- People applying to become medical residents in the United States speak a wide range of non-English languages, but many aren't the languages spoken by patients with limited English skills, according to a research letter published in the Dec. 10 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Six-Week Antibiotic Tx Effective for Diabetic Foot Osteomyelitis

WEDNESDAY, Dec. 10, 2014 (HealthDay News) -- For patients with diabetic foot osteomyelitis (DFO), six weeks of antibiotic therapy seems as effective as 12 weeks of treatment, according to a study published online Nov. 20 in Diabetes Care.

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Higher Paid Docs Earn More Money From More Procedures

TUESDAY, Dec. 9, 2014 (HealthDay News) -- High-income doctors make more money by ordering more procedures for each patient rather than by seeing more patients, according to an analysis of 2012 Medicare data published in a research letter Dec. 8 in JAMA Internal Medicine.

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Work-Hour Restrictions Have Not Improved Outcomes

TUESDAY, Dec. 9, 2014 (HealthDay News) -- Reducing medical residents' work hours hasn't improved mortality rates, hospital readmission rates, or outcomes of surgery, according to two new studies published in the Dec. 10 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Docs Trained in High-Cost Areas Practice More Costly Medicine

TUESDAY, Dec. 9, 2014 (HealthDay News) -- Doctors who were trained in high-cost areas of the United States may be more likely to practice expensive medicine, a new study suggests; however, that effect gradually decreases over time. The study was published in the Dec. 10 issue of the Journal of the American Medical Association, a theme issue on medical education.

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Continued Metformin Beneficial for Diabetes With Cirrhosis

TUESDAY, Dec. 9, 2014 (HealthDay News) -- Continuation of metformin therapy may improve survival in diabetes patients who are diagnosed with cirrhosis, according to research published in the December issue of Hepatology.

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Tramadol Use May Up Risk of Hospitalization for Hypoglycemia

TUESDAY, Dec. 9, 2014 (HealthDay News) -- Tramadol use is associated with an increased risk of hypoglycemia requiring hospitalization, especially in the first 30 days of use, according to a study published online Dec. 8 in JAMA Internal Medicine.

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AMA: Starting Small Can Lead to Big Changes in Patient Lives

MONDAY, Dec. 8, 2014 (HealthDay News) -- A patient and her physician shared her story of health transformation during a special session at the 2014 American Medical Association (AMA) Interim Meeting in Dallas.

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Long-Term Effect of Gestational Diabetes Treatment Uncertain

MONDAY, Dec. 8, 2014 (HealthDay News) -- The effects of treatment of mild gestational diabetes mellitus (GDM) on long-term child health are unclear, according to research published online Nov. 20 in Diabetes Care.

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Premature Ejaculation Linked to Hypoglycemic Variability in T1DM

MONDAY, Dec. 8, 2014 (HealthDay News) -- Higher glycemic variability in the hypoglycemic domain is associated with premature ejaculation (PE) in young males with type 1 diabetes (T1DM), although prevalence of PE is similar for young males with and without T1DM, according to a study published online Nov. 26 in the Journal of Sexual Medicine.

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Metabolic Abnormalities Tied to Lower Urinary Tract Symptoms

MONDAY, Dec. 8, 2014 (HealthDay News) -- Metabolic abnormalities such as metabolic syndrome and insulin resistance are associated with lower urinary tract symptoms (LUTS), according to two studies published online Dec. 8 in BJU International.

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Peer Education Helpful for Diabetes Patients in Distress

FRIDAY, Dec. 5, 2014 (HealthDay News) -- Peer education improves mental status in type 2 diabetes patients who have emotional disorders, according to research published online Nov. 16 in the Journal of Diabetes Investigation.

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AMA: Social Determinants of Health to Be Taught in Med School

THURSDAY, Dec. 4, 2014 (HealthDay News) -- A new policy implemented by the American Medical Association (AMA) supports integrating more training on the social determinants of health into undergraduate medical education, according to a report published by the AMA.

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Low Testosterone Linked to Adverse Outcomes in T2DM

THURSDAY, Dec. 4, 2014 (HealthDay News) -- For men with type 2 diabetes, low serum testosterone seems to be implicated in adverse clinical outcomes, according to a review published online Nov. 3 in the Journal of Diabetes Investigation.

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Preconception Care Could Cut Pregestational Diabetes Burden

WEDNESDAY, Dec. 3, 2014 (HealthDay News) -- Universal preconception care (PCC) could reduce the health and cost burden associated with diagnosed and undiagnosed pregestational diabetes mellitus (PGDM), according to a study published online Oct. 28 in the American Journal of Obstetrics & Gynecology.

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Childhood Obesity Prevention Programs Impact LDL-C, HDL-C

WEDNESDAY, Dec. 3, 2014 (HealthDay News) -- Childhood obesity prevention programs are beneficial for low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), according to a systematic review and meta-analysis published in the December issue of Obesity Reviews.

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Hyperglycemia Linked to Reduced Muscle Strength

TUESDAY, Dec. 2, 2014 (HealthDay News) -- Hyperglycemia is associated with reduced muscle strength over time, according to a study published online Nov. 12 in Diabetes Care.

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Too Much Patient Care Tied to Faculty Members' Intent to Leave

TUESDAY, Dec. 2, 2014 (HealthDay News) -- Spending "far too much/too much" time/effort on patient care is associated with increased intent to leave the institution, according to research published in Academic Medicine.

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Midlife Diabetes Linked to Greater Cogntive Decline Later

TUESDAY, Dec. 2, 2014 (HealthDay News) -- Diabetes in midlife is associated with a greater decline in cognitive skills over 20 years, according to a new study published in the Dec. 2 issue of the Annals of Internal Medicine.

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Doctor Discusses Ways to Keep Morale in Medicine High

MONDAY, Dec. 1, 2014 (HealthDay News) -- Despite the many frustrations for doctors in medical practice, there are ways to keep morale high, according to an article published Nov. 20 in Medical Economics.

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Testosterone Tx Doesn't Up Prostate CA in Hypogonadal Men

MONDAY, Dec. 1, 2014 (HealthDay News) -- For hypogonadal men, long-term testosterone therapy seems not to be associated with increased incidence of prostate cancer, according to research published in The Journal of Urology.

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Many Physicians Report Their Incomes Have Plateaued

MONDAY, Dec. 1, 2014 (HealthDay News) -- Many physicians report that their personal income has not changed since last year, according to the results of the Physicians Practice 2014 Physicians Compensation Survey.

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Mortality Risk Up With Both Low and High HbA1c Levels

MONDAY, Dec. 1, 2014 (HealthDay News) -- Excess mortality risk is associated with both known diabetes and undiagnosed diabetes but not prediabetes, with lowest risk at HbA1c levels 5.4 to 5.6 percent and a significantly increased risk at ≤5.0 percent and ≥6.4 percent, according to a study published online Nov. 20 in Diabetes Care.

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