Data Support FDA Restrictions on Child Cough and Cold Medicines

Share this content:
Data Support FDA Restrictions on Child Cough and Cold Medicines
Data Support FDA Restrictions on Child Cough and Cold Medicines

FRIDAY, July 13, 2018 (HealthDay News) -- New research supports expanded restrictions on opioid-containing cough and cold medications (CCMs) for children, according to a short communication published recently in Clinical Toxicology.

Ian M. Paul, M.D., from the Penn State College of Medicine in Hershey, and colleagues characterized adverse events in children <12 years old associated with CCMs that include both an opioid (codeine or hydrocodone) and over-the-counter ingredient. Cases were identified from a safety surveillance program (January 2008 and December 2015).

The researchers found that 114 of the 7,035 cases reviewed (2 percent) involved an opioid-containing product. The adverse event was at least potentially related to the opioid ingredient in 98 cases (39 percent codeine; 61 percent hydrocodone). Three fatality cases involved CCMs with hydrocodone and an antihistamine. Somnolence, lethargy, and/or respiratory depression were more commonly reported among non-fatal hydrocodone cases versus non-fatal codeine cases (86 versus 61 percent; P = 0.005).

"Health care providers should never prescribe opioid-containing cough and cold products to children," Paul said in a statement. "Ever."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Approves First Customizable Insulin Pump

FDA Approves First Customizable Insulin Pump

Product works by delivering insulin under the skin at set or variable rates

Sepsis Common in Terminal Hospitalizations, Discharges

Sepsis Common in Terminal Hospitalizations, Discharges

Most common underlying causes of death in sepsis are solid and hematologic cancers, chronic heart disease

Fewer Older Men Assessed, Treated for Osteoporosis

Fewer Older Men Assessed, Treated for Osteoporosis

Fewer older men than women, even with higher risk, undergo DXA screening, 25(OH)D measurement

is free, fast, and customized just for you!




Already a member?

Sign In Now »