Cryotherapy May Prevent Chemo-Induced Neuropathy

Share this content:
Cryotherapy May Prevent Chemo-Induced Neuropathy
Cryotherapy May Prevent Chemo-Induced Neuropathy

FRIDAY, Oct. 20, 2017 (HealthDay News) -- Cryotherapy may be useful for preventing symptoms of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online Oct. 12 in the Journal of the National Cancer Institute.

Akiko Hanai, O.T.R., from Kyoto University in Japan, and colleagues evaluated the efficacy of cryotherapy for CIPN prevention among 36 breast cancer patients treated weekly with paclitaxel (80mg/m2 for one hour). Study participants wore frozen gloves and socks on the dominant side for 90 minutes, including the entire duration of drug infusion.

The incidence of objective and subjective CIPN signs was lower on the intervention side versus the control side. This held true for hand tactile sensitivity (odds ratio [OR], 20; 95 percent confidence interval [CI], 3.2 to 828.96; P < 0.001), foot tactile sensitivity (OR, infinite; 95 percent CI, 3.32 to infinite; P < 0.001), hand warm sense (OR, 9; 95 percent CI, 1.25 to 394.48; P = 0.02), foot warm sense (OR, 5; 95 percent CI, 1.07 to 46.93; P = 0.04), hand Patient Neuropathy Questionnaire (PNQ; OR, infinite; 95 percent CI, 3.32 to infinite; P < 0.001), and foot PNQ (OR, infinite; 95 percent CI, 2.78 to infinite; P < 0.001).

"Cryotherapy is useful for preventing both the objective and subjective symptoms of CIPN and resultant dysfunction," conclude the authors.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

WHO: Vaccine Hesitancy a Major Global Health Threat

WHO: Vaccine Hesitancy a Major Global Health Threat

Percentage of U.S. children 19 to 35 months who have not been vaccinated has quadrupled since 2001

FDA Down to 5 Weeks of Funding to Review New Drug Applications

FDA Down to 5 Weeks of Funding to ...

Agency cannot accept new fees or applications until the shutdown is over

FDA Approves First Generic Version of Epilepsy Drug Sabril

FDA Approves First Generic Version of Epilepsy Drug ...

Generic equivalents held to same vigorous manufacturing standards as brand-name drugs

is free, fast, and customized just for you!




Already a member?

Sign In Now »