Complications, Costs Up With Cardiac Sx in Opioid Use Disorder

Share this content:
Complications, Costs Up With Cardiac Sx in Opioid Use Disorder
Complications, Costs Up With Cardiac Sx in Opioid Use Disorder

WEDNESDAY, Dec. 26, 2018 (HealthDay News) -- Patients with opioid use disorder (OUD) undergoing cardiac surgery have increased complications and costs, according to a study published online Dec. 5 in JAMA Surgery.

Krish C. Dewan, from the Cleveland Clinic Foundation, and colleagues compared outcomes between cardiac surgery patients with OUD (11,359 patients) and without OUD (5,707,193 patients) from 1998 to 2013.

The researchers found that over 15 years there was an eightfold increase in the prevalence of OUD, from 0.06 percent in 1998 to 0.54 percent in 2013. Patients with OUD more often had valve and aortic operations (49.8 versus 16.4 percent; P < 0.001). Mortality was similar for patients with and without OUD in propensity-matched pairs (3.1 versus 4.0 percent; P = 0.12), while the incidence of major complications was higher for patients with OUD (67.6 versus 59.2 percent; P < 0.001). Significantly higher risks of blood transfusion (30.4 versus 25.9 percent; P = 0.002), pulmonary embolism (7.3 versus 3.8 percent; P < 0.001), mechanical ventilation (18.4 versus 15.7 percent; P = 0.02), and prolonged postoperative pain (2.0 versus 1.2 percent; P = 0.048) were seen for patients with OUD. They also had a significantly longer length of stay (median, 11 versus 10 days; P < 0.001) and higher cost per patient ($49,790 versus $45,216; P < 0.001).

"In urgent situations, patients need not be denied cardiac surgery because of their OUD status, although close postoperative monitoring is suggested," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »