Chronic Opioid Users May Wish to Taper Opioid Use

Share this content:
Chronic Opioid Users May Wish to Taper Opioid Use
Chronic Opioid Users May Wish to Taper Opioid Use

WEDNESDAY, Feb. 21, 2018 (HealthDay News) -- Many patients with non-cancer-related chronic pain prescribed long-term opioids may wish to taper their opioid use, according to a research letter published online Feb. 19 in JAMA Internal Medicine.

Beth D. Darnall, Ph.D., from the Stanford University School of Medicine in Palo Alto, Calif., and colleagues conducted a study in which patients with non-cancer-related chronic pain prescribed long-term opioids at a community pain clinic were given education about the benefits of opioid reduction. Physicians offered to partner with patients to gradually reduce their dosages of opioids over four months. Seventy-five percent of 110 eligible patients (82 patients) agreed to taper their opioid dosages; participants received a self-help book and an individually designed taper.

The researchers found that 38 percent of the 82 enrolled patients did not complete a four-month follow-up survey and were considered to have dropped out. There was a negative correlation for depression and a positive correlation for baseline marijuana use with study completion. The baseline median morphine equivalent daily dose (MEDD) was 288 mg among study completers, with a median six-year duration of opioid use. The median MEDD was reduced to 150 mg after four months. Opioid reduction was not associated with increased pain intensity or pain interference.

"Our findings suggest that a substantial fraction of patients at a pain clinic may wish to engage in voluntary opioid tapering," the authors write.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Bayer Stops U.S. Sale of Essure Birth Control Implant

Bayer Stops U.S. Sale of Essure Birth Control ...

Problems with device include chronic pain and perforations of the uterus and fallopian tubes

C.S. Mott Poll Addresses Child Safety at Amusement Parks

C.S. Mott Poll Addresses Child Safety at Amusement ...

2016 saw U.S. emergency departments deal with 30,000 injuries linked to amusement parks, carnivals

Greening Vacant Land Improves Neighborhood Mental Health

Greening Vacant Land Improves Neighborhood Mental Health

Cleaning up vacant lots in resource-limited urban settings can aid residents' mental health

is free, fast, and customized just for you!




Already a member?

Sign In Now »