Change in BMI During Puberty Tied to Later Heart Failure Risk

Share this content:
Change in BMI During Puberty Tied to Later Heart Failure Risk
Change in BMI During Puberty Tied to Later Heart Failure Risk

THURSDAY, March 29, 2018 (HealthDay News) -- Change in body mass index (BMI) to overweight during puberty significantly increases men's risk of heart failure later in life, according to a study published online March 12 in the Journal of Internal Medicine.

Jenny M. Kindblom, M.D., Ph.D., from the University of Gothenburg in Sweden, and colleagues used data from the BMI Epidemiology Study to assess the association between childhood BMI and BMI change during puberty and risk of adult heart failure. Researchers collected data on 37,670 men born between 1945 and 1961 and followed until December 2013.

The researchers found that BMI change during puberty was independently associated with risk of heart failure in a nonlinear J-shaped manner, regardless of childhood BMI. Compared with participants in the lowest quartile of BMI change, those in the upper quartile during puberty had more than a two-fold increase in risk of heart failure (hazard ratio [HR], 2.29; 95 percent confidence interval [CI], 1.68 to 3.12). Compared with boys who were neither overweight during childhood or puberty, boys developing overweight during puberty had increased risk of heart failure (HR, 3.14; 95 percent CI, 2.25 to 4.38), but not boys who were overweight in childhood who normalized weight during puberty (HR, 1.12; 95 percent CI, 0.63 to 2.00).

"BMI change during puberty is a novel risk factor for adult heart failure in men," the authors write.

Abstract/Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »