Cataract Risk Not Down With Long-Tem Selenium, Vitamin E

This article originally appeared here.
Share this content:
Cataract Risk Not Down With Long-Tem Selenium, Vitamin E
Cataract Risk Not Down With Long-Tem Selenium, Vitamin E

THURSDAY, Jan. 8, 2015 (HealthDay News) -- Long-term supplementation with selenium or vitamin E is not associated with a reduction in the risk of age-related cataract among men, according to a study published in the January issue of JAMA Ophthalmology.

William G. Christen, Sc.D., from Brigham and Women's Hospital in Boston, and colleagues examined the effect of long-term supplementation with selenium and vitamin E on the incidence of cataract. Data were collected from the Selenium and Vitamin E Cancer Prevention Trial (SELECT) involving men aged 50 years and older for African-American participants and 55 years and older for all other men. A total of 11,267 SELECT participants participated in the SELECT Eye Endpoints ancillary study.

The researchers identified 389 cases of cataract during a mean of 5.6 years of treatment and follow-up. There was no significant difference in the number of cataracts in the selenium versus the no selenium group (185 versus 204; hazard ratio, 0.91; 95 percent confidence interval, 0.75 to 1.11; P = 0.37). No difference was seen in the vitamin E treated group versus the placebo group (197 versus 192 cases; hazard ratio, 1.02; 95 percent confidence interval, 0.84 to 1.25; P = 0.81). Results were similar for cataract extraction.

"These data from a large cohort of apparently healthy men indicate that long-term daily supplementation with selenium and/or vitamin E is unlikely to have a large beneficial effect on age-related cataract," the authors write.

One author disclosed financial ties to Pfizer related to vitamins. Study agents, packaging, and multivitamins were provided by nutritional companies.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Critics Demand Stop to 'Guinea Pig' Sepsis Clinical Trial

Critics Demand Stop to 'Guinea Pig' Sepsis Clinical ...

Clovers trial seeks to determine which IV fluids, vasopressors combo works best to curb sepsis

Education Can Up Emotional Intelligence in Residents

Education Can Up Emotional Intelligence in Residents

Increase in total EI median scores, stress management composite score after intervention

Cancer-Related Gene Variations Frequently Reclassified

Cancer-Related Gene Variations Frequently Reclassified

24.9 percent of variants of uncertain significance were reclassified at a single commercial laboratory

is free, fast, and customized just for you!




Already a member?

Sign In Now »