Case Volume Affects Mortality for Immunosuppressed With Sepsis

Share this content:
Case Volume Affects Mortality for Immunosuppressed With Sepsis
Case Volume Affects Mortality for Immunosuppressed With Sepsis

FRIDAY, June 8, 2018 (HealthDay News) -- At hospitals with the lowest volume of immunosuppressed patients with sepsis, the risk of death from sepsis due to a suppressed immune state is highest, according to a study published online June 1 in the Annals of the American Thoracic Society.

Jared A. Greenberg, M.D., from the Rush University Medical Center in Chicago, and colleagues characterized patients with sepsis at hospitals according to immune state. Variation in the odds of in-hospital death from sepsis due to a suppressed immune state was examined based on the average volume of immunosuppressed patients with sepsis each year.

The researchers identified 350,183 patients with sepsis at 60 hospitals from 2010 to 2012. Compared with non-immunosuppressed patients with sepsis, immunosuppressed patients with sepsis at the 15 hospitals in the first quartile had increased odds of in-hospital death (adjusted odds ratio, 1.38). For patients at hospitals in the second, third, and fourth quartiles, the odds of in-hospital death for immunosuppressed patients with sepsis relative to non-immunosuppressed patients with sepsis was similar. The adjusted odds of death from sepsis due to a suppressed immune state (odds ratio, 1.21) was significantly lower for these 45 hospitals analyzed as a group relative to that for the patients at the 15 hospitals in the first quartile (P = 0.004 for difference).

"The risk of death from sepsis due to a suppressed immune state was greatest at hospitals with the lowest volume of immunosuppressed patients with sepsis," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC Identifies Drugs Frequently Involved in Drug Overdose Deaths

CDC Identifies Drugs Frequently Involved in Drug Overdose ...

Oxycodone, heroin, and fentanyl ranked first in 2011, 2012-2015, 2016; cocaine ranked second or third

2017 Saw Slowing in National Health Care Spending

2017 Saw Slowing in National Health Care Spending

Slower growth in health care spending mainly due to use and intensity of goods and services

Inflammatory Bowel Disease, Prostate Cancer Linked

Inflammatory Bowel Disease, Prostate Cancer Linked

At age 60, men with inflammatory bowel disease have higher values of prostate-specific antigen

is free, fast, and customized just for you!




Already a member?

Sign In Now »