Cardiometabolic Risk Up With Tourette, Chronic Tic Disorder

Share this content:
Cardiometabolic Risk Up With Tourette, Chronic Tic Disorder
Cardiometabolic Risk Up With Tourette, Chronic Tic Disorder

TUESDAY, Jan. 15, 2019 (HealthDay News) -- Patients with Tourette syndrome (TS) or chronic tic disorder (CTD) have an increased risk for developing at least one metabolic or cardiovascular disorder, according to a study published online Jan. 14 in JAMA Neurology.

Gustaf Brander, from the Karolinska Institutet in Stockholm, and colleagues examined the risk for metabolic and cardiovascular disorders among individuals with TS or CTD during 40 years. Data were included for 7,804 individuals with a registered diagnosis of TS or CTD in specialist care within a cohort of 14,045,026 individuals.

The researchers found that compared with the general population, individuals with TS or CTD had a higher risk for any metabolic or cardiovascular disorders (hazard ratio adjusted by sex and birth year, 1.99); the risk was also increased compared with sibling controls (adjusted hazard ratio for any disorder, 1.37). Risks were increased for obesity, diabetes, and circulatory system diseases (adjusted hazard ratios, 2.76, 1.67, and 1.76, respectively). The risks were evident from childhood (significant difference by age 8 years) and were significantly reduced when individuals with comorbid attention-deficit/hyperactivity disorder were excluded (adjusted hazard ratio, 1.52). Patients with a longer duration of antipsychotic treatment (more than one year) had significantly lower risks for metabolic and cardiovascular disorders than those not taking antipsychotics.

"The results expand our understanding of the broader health consequences of TS and CTD and have direct clinical implications across health services," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Head Says Feds May Intervene to Cut Vaccine Exemptions

FDA Head Says Feds May Intervene to Cut ...

If states do not change lax vaccine laws, federal authorities may be forced to take action

New Kaiser Permanente Medical School Plans to Waive Tuition

New Kaiser Permanente Medical School Plans to Waive ...

School will waive all tuition for the full four years of school for its first five classes

Experimental Test May Quickly Diagnose Sepsis

Experimental Test May Quickly Diagnose Sepsis

Microelectrode device analyzes a patient's blood, provides results in as quickly as 2.5 minutes

is free, fast, and customized just for you!




Already a member?

Sign In Now »