Calquence Approved for Mantle Cell Lymphoma

Share this content:
Calquence Approved for Mantle Cell Lymphoma
Calquence Approved for Mantle Cell Lymphoma

TUESDAY, Oct. 31, 2017 (HealthDay News) -- Calquence (acalabrutinib) has been approved by the U.S. Food and Drug Administration to treat adults with mantle cell lymphoma.

Calquence is a Bruton tyrosine kinase (BTK) inhibitor. The drug was evaluated in a clinical study of 124 people with mantle cell lymphoma who had received at least one prior treatment. Some 81 percent of trial participants given the drug had a complete or partial response.

Common adverse effects include headache, diarrhea, bruising, myalgia, anemia, thrombocytopenia and neutropenia. Serious adverse reactions include hemorrhage, infections, atrial fibrillation, and second primary malignancies, the FDA said.

"For patients who have not responded to treatment or have relapsed, Calquence provides a new treatment option that has shown high rates of response for some patients in initial studies," Richard Pazdur, M.D., director of the FDA's Oncology Center of Excellence, said in a statement.

The FDA granted accelerated approval of Calquence to AstraZeneca, based in the United Kingdom.

More Information

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

'Aggressive Steps' Needed to Stop Adolescent Use of E-Cigarettes

'Aggressive Steps' Needed to Stop Adolescent Use of ...

U.S. Surgeon General issues a call to action for parents, teachers, and health professionals

Exercise Linked to Reduced Mortality for Patients With Cancer

Exercise Linked to Reduced Mortality for Patients With ...

Mortality rate lower for habitually active patients and for those who started exercising after diagnosis

Hospitalizations Up for Homeless From 2007 to 2013

Hospitalizations Up for Homeless From 2007 to 2013

Homeless individuals hospitalized more often for mental illness, substance use disorder

is free, fast, and customized just for you!




Already a member?

Sign In Now »