CABG May Be Best for Patients With DM, LV Dysfunction

Share this content:
CABG May Be Best for Patients With DM, LV Dysfunction
CABG May Be Best for Patients With DM, LV Dysfunction

TUESDAY, Feb. 27, 2018 (HealthDay News) -- Coronary artery bypass grafting (CABG) is associated with a significant reduction in major adverse cardiac and cerebrovascular events and mortality compared with percutaneous coronary intervention (PCI) among patients with diabetes mellitus (DM), multivessel coronary artery disease (CAD), and left ventricular dysfunction (LVD), according to a study published in the Feb. 27 issue of the Journal of the American College of Cardiology.

Jeevan Nagendran, M.D., Ph.D., from the University of Alberta in Canada, and colleagues evaluated whether treatment with PCI or CABG leads to improved outcomes in patients with DM, CAD, and LVD. Patients in the study underwent isolated CABG without a concomitant procedure or PCI between Jan. 1, 2004, and March 31, 2016. The researchers included 2,837 patients in the study analysis and 1,738 in propensity-score matched analysis.

The researchers found that compared to CABG, PCI was associated with a higher risk for major adverse cardiac and cerebrovascular events at five years in patients with ejection fraction (EF) 35 to 49 percent and <35 percent (51 versus 28 percent and 61 versus 29 percent, respectively). PCI was also associated with an increased risk for death in both of the EF cohorts at five years (26 versus 16 percent and 35 versus 19 percent, respectively). The stroke rate was similar for PCI and CABG in both EF cohorts. In the EF <35 percent cohort, PCI was associated with an increased rate of myocardial infarction. In patients treated with PCI compared with CABG in both the EF cohorts, repeat revascularization occurred more frequently.

"At long-term follow-up, patients with CAD, DM, and LVD treated with CABG exhibited a significantly lower incidence of major adverse cardiac and cerebrovascular events and better long-term survival over PCI, without a higher risk for stroke," the authors write.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Cognitive Disability Most Prevalent Type in Young Adults

Cognitive Disability Most Prevalent Type in Young Adults

Disability-specific disparities prevalent in access to health care, especially for young, middle-aged adults

Declines in Life Expectancy in Many High-Income Countries

Declines in Life Expectancy in Many High-Income Countries

And increase in midlife death rates across racial and ethnic groups in the United States

Tobacco Content Still Common on U.K. Prime-Time Television

Tobacco Content Still Common on U.K. Prime-Time Television

Tobacco content occurred in 33 percent of all programs; 8 percent of all adverts, trailer breaks

is free, fast, and customized just for you!




Already a member?

Sign In Now »