Broader Statin Use Improves Atherosclerotic CVD Prevention

Share this content:
Broader Statin Use Improves Atherosclerotic CVD Prevention
Broader Statin Use Improves Atherosclerotic CVD Prevention

TUESDAY, Jan. 2, 2018 (HealthDay News) -- Guidelines that recommend statins for more people for primary prevention of atherosclerosis are likely to prevent more atherosclerotic cardiovascular disease (ASCVD) events than guidelines that recommend fewer people take statins, according to a study published online Jan. 1 in the Annals of Internal Medicine.

Martin Bødtker Mortensen, M.D., Ph.D., from Aarhus University Hospital, and Børge Grønne Nordestgaard, M.D., from Herlev and Gentofte Hospital, both in Denmark, compared the utility of recently published guidelines issued by five major organizations for statin use to prevent ASCVD. The effectiveness of the different guidelines was estimated in an observational study of actual ASCVD events during 10 years in a population of 45,750 Danish adults aged 40 to 75 years who did not use statins and did not have ASCVD at baseline.

The researchers found that the percentage of participants eligible for statins was 44, 42, 40, 31, and 15 percent, respectively, for the Canadian Cardiovascular Society (CCS) guideline, the American College of Cardiology/American Heart Association (ACC/AHA) guideline, the United Kingdom's National Institute for Health and Care Excellence (NICE) guideline, the U.S. Preventive Services Task Force (USPSTF) guideline, and the European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guideline. Statin use for 10 years could have prevented an estimated 34, 34, 32, 27, and 13 percent of ASCVD events with the CCS, ACC/AHA, NICE, USPSTF, and ESC/EAS guidelines, respectively.

"Guidelines recommending that more persons use statins for primary prevention of ASCVD should prevent more events than guidelines recommending use by fewer persons," the authors write.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA: Gout Drug Uloric Increases Risk of Death

FDA: Gout Drug Uloric Increases Risk of Death

Medication is associated with increased risk of heart-related death and death from all causes

Since Early 2000s, Overdose Death Rates Are Highest in U.S.

Since Early 2000s, Overdose Death Rates Are Highest ...

U.S. was not an outlier in terms of drug overdose mortality prior to the early 2000s

National Health Spending Set to Increase 5.5 Percent Annually

National Health Spending Set to Increase 5.5 Percent ...

Long-observed demographic and economic factors expected to drive growth in health spending

is free, fast, and customized just for you!




Already a member?

Sign In Now »