Brain Measures Tied to Atrial Pressure in Valvular Heart Dz

Share this content:
Brain Measures Tied to Atrial Pressure in Valvular Heart Dz
Brain Measures Tied to Atrial Pressure in Valvular Heart Dz

TUESDAY, Nov. 7, 2017 (HealthDay News) -- For patients with chronic valvular heart disease, white matter hyperintensity (WMH) volume is associated with mean right atrial (RA) pressure, according to a study published online Nov. 6 in JAMA Neurology.

Woo-Jin Lee, M.D., from Seoul National University Hospital in South Korea, and colleagues examined the correlation between chronically altered cardiac hemodynamics and severity of cerebral WMH in 303 patients diagnosed with severe chronic valvular heart disease. Two hundred thirty-two patients were included in the final analyses.

The researchers found that 63.4 percent of patients were classified as having a disease involving the mitral valve; 40.1 percent, the aortic valve; 15.9 percent, the tricuspid valve; and 1.7 percent, the pulmonary valve. WMH volume was linearly associated with mean RA pressure (B coefficient, 0.702; 95 percent confidence interval, 0.373 to 1.031; P = 0.001) along with age (B coefficient, 0.145; 95 percent confidence interval, 0.029 to 0.261; P = 0.01) and mean aortic pressure (B coefficient, 0.112; 95 percent confidence interval, 0.034 to 0.19; P = 0.005) after adjustment for the type and mechanism of valve disease and clinical, echocardiographic, and/or other catheterization parameters.

"Mean RA pressure was independently associated with the WMH volume in chronic valvular heart disease," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »