Both Abstinence and High Alcohol Use Linked to Dementia

Share this content:
Both Abstinence and High Alcohol Use Linked to Dementia
Both Abstinence and High Alcohol Use Linked to Dementia

TUESDAY, Aug. 14, 2018 (HealthDay News) -- Abstinence in midlife and consumption of more than 14 units of alcohol per week are associated with increased risk of dementia, according to a study published online Aug. 1 in The BMJ.

Séverine Sabia, Ph.D., from the Université Paris-Saclay, and colleagues conducted a prospective cohort study involving 9,087 participants aged 35 to 55 years at study inception. Participants were followed for a mean of 23 years for incident dementia.

During follow-up, the researchers identified 397 cases of dementia. The risk of dementia was higher with abstinence in midlife (hazard ratio, 1.47) compared with consumption of one to 14 units per week. Among those drinking more than 14 units/week, there was a 17 percent increase in dementia risk with a seven-unit increase in alcohol consumption. Increased dementia risk was also seen with CAGE score >2 and alcohol-related hospital admission (hazard ratios, 2.19 and 4.28, respectively). Compared with long-term consumption of one to 14 units per week, there was an association for increased risk of dementia with alcohol consumption trajectories from midlife to early old age of long-term abstinence, decrease in consumption, and long-term consumption above 14 units per week (hazard ratios, 1.74, 1.55, and 1.40, respectively). The excess risk of dementia associated with abstinence was partly explained by cardiometabolic disease over follow-up.

"The risk of dementia was increased in people who abstained from alcohol in midlife or consumed >14 units/week," the authors write.

Abstract/Full Text
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Wait Times Have Improved in VA Health Care System

Wait Times Have Improved in VA Health Care ...

Wait times similar to private sector in 2014 but shorter overall and in some specialties in 2017

Medication Treatment for Substance Abuse Up in Facilities

Medication Treatment for Substance Abuse Up in Facilities

2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016

Mindfulness, Stress Linked to Menopausal Symptoms

Mindfulness, Stress Linked to Menopausal Symptoms

Link between mindfulness and symptoms more robust in women experiencing higher stress

is free, fast, and customized just for you!




Already a member?

Sign In Now »