Baseline ALT, AST Frequently Assessed With Statin Initiation

This article originally appeared here.
Share this content:
Baseline ALT, AST Frequently Assessed With Statin Initiation
Baseline ALT, AST Frequently Assessed With Statin Initiation

MONDAY, July 18, 2016 (HealthDay News) -- Most Medicare fee-for-service beneficiaries with dyslipidemia who initiate statins undergo baseline alanine aminotransferase (ALT) and aspartate aminotransferase (AST) testing, according to a study published in the Aug. 1 issue of The American Journal of Cardiology.

Matthew L. Maciejewski, Ph.D., from the Durham Veterans Affairs Medical Center in North Carolina, and colleagues examined disparities in guideline-concordant baseline laboratory testing and abnormal laboratory values in a retrospective cohort of 76,868 Medicare fee-for-service beneficiaries from 10 states. Participants had dyslipidemia and initiated a statin from July 1 to Nov. 30, 2011.

The researchers found that baseline laboratory testing rates were 89.3 and 88.8 percent for ALT and AST, respectively. The likelihood of having ALT and AST testing was increased slightly for older adults if they were dually enrolled in Medicaid (relative risk, 1.01) or had multiple chronic conditions compared with none or one condition (relative risks, 1.03, 1.08, and 1.14 for two to three, four to five, and six or more conditions, respectively). Non-Hispanic blacks were less likely than non-Hispanic whites to receive baseline testing (odds ratio, 0.97). Males were less likely than female beneficiaries to receive testing (odds ratio, 0.99). Abnormal values were rarely observed.

"In conclusion, ALT and AST assessment after statin initiation was commonly done as recommended, and there were negligible disparities in testing rates for beneficiaries," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Ground Beef Recalled After E. Coli Outbreak

Ground Beef Recalled After <i>E. Coli</i> Outbreak

Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.

Prevalence of Alzheimer's, Related Dementia Set to Double

Prevalence of Alzheimer's, Related Dementia Set to Double

Alzheimer's disease and related dementias burden is expected to increase to 3.3 percent in 2060

Long-Term Outcomes of Breast Implants Explored

Long-Term Outcomes of Breast Implants Explored

Higher rates of Sjogren syndrome, scleroderma, RA, stillbirth, melanoma for silicone implants

is free, fast, and customized just for you!




Already a member?

Sign In Now »