Autosomal Dominant Polycystic Kidney Dz Pain Often Refractory

This article originally appeared here.
Share this content:
Autosomal Dominant Polycystic Kidney Dz Pain Often Refractory
Autosomal Dominant Polycystic Kidney Dz Pain Often Refractory

(HealthDay News) -- The etiology of pain in autosomal dominant polycystic kidney disease is complex, and management of pain should be approached in a stepwise manner, according to a review published in the May issue of The Journal of Urology.

Matthew W. Tellman, from the Indiana University School of Medicine in Indianapolis, and colleagues conducted a systematic literature review of the etiology and management of pain in autosomal dominant polycystic kidney disease and anatomy of renal innervation.

The researchers found that for most patients with autosomal dominant polycystic kidney disease, pain occurs due to renal, hepatic, and mechanical origins. Patients may experience different types of pain complicating confirmation of etiology. Anatomical and histological assessment of renal innervation can help elucidate the mechanisms that can lead to renal pain. A stepwise approach is recommended for management of pain in autosomal dominant polycystic kidney disease. Due to the high incidence of acute causes of renal pain in autosomal dominant polycystic kidney disease, these must be ruled out first. Non-opioid analgesics and conservative interventions can be used first for chronic pain, before considering opioid analgesics. Surgical interventions such as renal cyst decortication, renal denervation, and nephrectomy can target pain from persistent renal or hepatic cysts.

"Chronic pain in patients with autosomal dominant polycystic kidney disease is often refractory to conservative, medical, and other noninvasive treatments," the authors write.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Wildfire Smoke Causing Poor Air Quality in U.S. Pacific Northwest

Wildfire Smoke Causing Poor Air Quality in U.S. ...

Air pollution advisories, air quality alerts issued for Washington, Oregon

Odds of Death Up With Exposure to Pregabalin, Opioids

Odds of Death Up With Exposure to Pregabalin, ...

Dose-response association with highest odds of opioid-related death with high-dose pregabalin

NYU Becomes First Medical School to Cover All Tuition

NYU Becomes First Medical School to Cover All ...

Full-tuition scholarships, regardless of need, offered to all new and current medical students

is free, fast, and customized just for you!




Already a member?

Sign In Now »