Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

Share this content:
Artificial Pancreas Treatment Efficacious for Type 1 Diabetes
Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

THURSDAY, April 19, 2018 (HealthDay News) -- For patients with type 1 diabetes, artificial pancreas treatment is efficacious, increasing the proportion of time spent in the near normoglycemic range, according to a study published online April 18 in The BMJ.

Eleni Bekiari, M.D., Ph.D., from the University of Thessaloniki in Greece, and colleagues conducted a systematic review and meta-analysis to examine the efficacy and safety of artificial pancreas treatment in non-pregnant outpatients with type 1 diabetes. Forty randomized controlled trials with 1,027 participants and data for 44 comparisons were analyzed.

The researchers found that 35 of the comparisons examined a single-hormone artificial pancreas system, while nine assessed a dual-hormone system. A low risk of bias was seen in only nine studies. Artificial pancreas use was associated with a significantly higher proportion of time in the near normoglycemic range, both overnight (weighted mean difference, 15.15 percent) and over a 24-hour period (9.62 percent). A favorable effect was seen with the artificial pancreas system for the proportion of time with sensor glucose level above 10 mmol/L or below 3.9 mmol/L over 24 hours compared with control treatment (−8.52 and −1.49 percent, respectively). Sensitivity analyses verified the robustness of the findings.

"Artificial pancreas systems are an efficacious and safe approach for treating outpatients with type 1 diabetes," the authors write.

Several authors disclosed financial ties to the pharmaceutical and medical device industries.

Abstract/Full Text
Editorial

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA: Gout Drug Uloric Increases Risk of Death

FDA: Gout Drug Uloric Increases Risk of Death

Medication is associated with increased risk of heart-related death and death from all causes

Since Early 2000s, Overdose Death Rates Are Highest in U.S.

Since Early 2000s, Overdose Death Rates Are Highest ...

U.S. was not an outlier in terms of drug overdose mortality prior to the early 2000s

National Health Spending Set to Increase 5.5 Percent Annually

National Health Spending Set to Increase 5.5 Percent ...

Long-observed demographic and economic factors expected to drive growth in health spending

is free, fast, and customized just for you!




Already a member?

Sign In Now »