April 2018 Briefing - Gastroenterology

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Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for April 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Liver-Kidney Recipients Have Donor-Specific Hypo-Responses

MONDAY, April 30, 2018 (HealthDay News) -- Simultaneous liver-kidney transplant recipients' peripheral blood cells have unique phenotypic and functional characteristics that are associated with donor-specific hypo-alloresponsiveness, according to a study published online April 12 in Kidney International.

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New Clinic Satisfaction Tool Provides Real-Time Feedback

THURSDAY, April 26, 2018 (HealthDay News) -- A new clinic satisfaction tool improves communication and provides real-time feedback, according to a study published online April 14 in Neurosurgery.

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Potentially Inappropriate Meds Use Prevalent in Cancer Patients

FRIDAY, April 27, 2018 (HealthDay News) -- Potentially inappropriate medication (PIM) use is relatively prevalent among patients with breast or colorectal cancer, though it is not associated with most adverse outcomes, according to a study published online April 24 in Cancer.

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Improvement in Race-Based Disparities in Years of Life Lost

THURSDAY, April 26, 2018 (HealthDay News) -- From 1990 to 2014 there was a decrease in race-based disparities in years of life lost (YLL) in the United States, according to a study published online April 25 in PLOS ONE.

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Saturday Is National Prescription Drug Take Back Day

THURSDAY, April 26, 2017 (HealthDay News) -- The U.S. Drug Enforcement Administration and local agencies are holding the 15th National Prescription Drug Take Back Day across the country this Saturday, April 28.

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Medicare Requiring Hospitals to Post Prices Online

WEDNESDAY, April 25, 2018 (HealthDay News) -- U.S. hospitals will have to post their standard prices online and make it easier for patients to access their electronic medical records, Medicare officials said Tuesday.

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IBD Associated With Increased Incidence of Parkinson's Disease

WEDNESDAY, April 25, 2018 (HealthDay News) -- Patients with inflammatory bowel disease (IBD) have increased incidence of Parkinson's disease (PD), which is attenuated with anti-tumor necrosis factor (TNF) therapy, according to a study published online April 23 in JAMA Neurology.

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Alcohol Intake May Influence Oral Microbiome Composition

TUESDAY, April 24, 2018 (HealthDay News) -- Alcohol consumption, specifically heavy drinking, may influence the oral microbiome composition, according to a study published online April 24 in Microbiome.

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Flexible Sigmoidoscopy Cuts CRC Incidence, Mortality in Men

MONDAY, April 23, 2018 (HealthDay News) -- Flexible sigmoidoscopy screening is associated with reduced colorectal cancer (CRC) incidence and mortality in men, but not women, according to a study published online April 24 in the Annals of Internal Medicine.

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Factors ID'd to Predict Fatty Liver in Obese Teens

MONDAY, April 23, 2018 (HealthDay News) -- Ethnicity/race, markers of insulin resistance, and genetic factors might help identify obese youth at risk for developing fatty liver, according to a study published online April 17 in Hepatology.

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Patients Prefer Doctors Who Engage in Face-to-Face Visits

MONDAY, April 23, 2018 (HealthDay News) -- Patients prefer physicians who engage in face-to-face (F2F) clinic visits, rather than those using an examination room computer (ERC), according to a research letter published online April 19 in JAMA Oncology.

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Colon Cancer Survival Varies by Insurance Type

FRIDAY, April 20, 2018 (HealthDay News) -- Compared to patients with private insurance, colon cancer survival is lower for patients with no insurance or with Medicaid, according to a study published in the May issue of Diseases of the Colon & Rectum.

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Prescribing of Gluten-Free Foods Declining in England

THURSDAY, April 19, 2018 (HealthDay News) -- Recent policy changes have led to a decline in the prescribing of gluten-free foods in England, according to research published online April 16 in BMJ Open.

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Opiate Use Linked to Early Mortality in IBD Patients

WEDNESDAY, April 18, 2018 (HealthDay News) -- Heavy use of opiates among patients with inflammatory bowel diseases (IBD) is tied to increased risk of premature all-cause death, according to a study published in the April issue of Clinical Gastroenterology and Hepatology.

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C. Difficile Risk Higher With Stoma Reversal Versus Colectomy

WEDNESDAY, April 18, 2018 (HealthDay News) -- Patients who undergo elective stoma reversal have a higher incidence of postoperative Clostridium difficile infection versus patients who undergo elective colectomy, according to a study published in the May issue of Diseases of the Colon & Rectum.

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Calcium Channel Blockers May Up Pancreatic Cancer Risk in Women

TUESDAY, April 17, 2018 (HealthDay News) -- Use of short-acting calcium channel blockers (CCBs) is associated with increased risk of pancreatic cancer in postmenopausal women, according to a study presented at the annual meeting of the American Association for Cancer Research, held from April 14 to 18 in Chicago.

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Males With BRCA Mutations Have Increased Risk of Certain Cancers

TUESDAY, April 17, 2018 (HealthDay News) -- Males with BRCA mutations have increased incidence of malignant disease, specifically prostate, melanoma, pancreas, and breast cancers, according to a research letter published online April 12 in JAMA Oncology.

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Metabolic Syndrome Common With Chronic Hep B Infection

TUESDAY, April 17, 2018 (HealthDay News) -- Metabolic syndrome (MetS) is prevalent among patients with chronic hepatitis B (HBV) infection, according to a study published online March 29 in Diabetes Care.

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Similar Outcomes for Transplant With Overdose-Death Donors

MONDAY, April 16, 2018 (HealthDay News) -- Transplantation of organs from overdose-death donors (ODDs) is associated with similar five-year patient survival and graft survival as organs from trauma-death donors (TDDs) and medical-death donors (MDDs), according to a study published online April 17 in the Annals of Internal Medicine.

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Recommendations Developed on Gender Equity in Medicine

MONDAY, April 16, 2018 (HealthDay News) -- In a position paper published online April 17 in the Annals of Internal Medicine, recommendations are provided aimed at addressing gender equity in physician compensation and career advancement opportunities.

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TFs Operate Across Gene Loci Within Disease Phenotypes

MONDAY, April 16, 2018 (HealthDay News) -- Transcription factors (TFs) seem to operate across gene loci, according to a study published online April 16 in Nature Genetics.

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Volumetric Laser Endomicroscopy Helps ID Barrett's Regions

MONDAY, April 16, 2018 (HealthDay News) -- Volumetric laser endomicroscopy (VLE) users can identify regions of interest for potential Barrett's esophagus (BE) dysplasia with a high degree of agreement, according to a study published online April 6 in the Journal of Gastroenterology and Hepatology.

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Nonoptimized Drug Therapy Costs More Than $500 Billion Annually

MONDAY, April 16, 2018 (HealthDay News) -- The estimated annual cost of drug-related morbidity and mortality resulting from nonoptimized medication therapy is more than half a trillion dollars in the United States, according to a study published online March 26 in the Annals of Pharmacotherapy.

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Adherence to ACS Guidelines Linked to Survival in Colon Cancer

FRIDAY, April 13, 2018 (HealthDay News) -- Adherence to the American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors (ACS guidelines) is associated with improved survival for patients with stage III colon cancer, according to a study published online April 12 in JAMA Oncology.

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Recent Years Saw Increase in Burden of Prior Authorization

THURSDAY, April 12, 2018 (HealthDay News) -- The burden of prior authorization (PA) has increased over the past five years, and 92 percent of physicians report associated delays in access to care, according to the results of a survey published by the American Medical Association (AMA).

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Increased Prevalence of Depression, Anxiety After CRC

THURSDAY, April 12, 2018 (HealthDay News) -- The prevalence of depression and anxiety are increased among survivors of colorectal cancer (CRC), according to a study published online April 6 in Cancer.

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Higher Mortality Risk Seen for 'Night Owls'

THURSDAY, April 12, 2018 (HealthDay News) -- Individuals with a later chronotype have increased mortality risk, according to a study published online April 12 in Chronobiology International.

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Suggestions Offered to Reduce Physician Frustration With EHRs

TUESDAY, April 10, 2018 (HealthDay News) -- Changes can be implemented to help reduce physician frustration with electronic health records (EHRs), according to an article published in Medical Economics.

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Considerable Differences in Burden of Disease at State Level

TUESDAY, April 10, 2018 (HealthDay News) -- There are considerable differences in the burden of disease at the state level, according to a study published in the April 10 issue of the Journal of the American Medical Association.

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DPP-4I Not Tied to Increased Risk of Acute Pancreatitis in Seniors

TUESDAY, April 10, 2018 (HealthDay News) -- For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care.

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Whole Body CT Doesn't Cut Mortality in Peds Blunt Trauma

TUESDAY, April 10, 2018 (HealthDay News) -- Whole body computed tomography (WBCT) is not associated with reduced mortality compared with a selective CT approach among children with blunt trauma, according to a study published online April 9 in JAMA Pediatrics.

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Interns' Schedule Takes Toll on Sleep, Physical Activity, Mood

FRIDAY, April 6, 2018 (HealthDay News) -- New interns' intense and changing schedules take a toll on sleep, activity, and mood, according to a study published online March 14 in the Journal of General Internal Medicine.

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Obesity Can Negatively Effect Liver in Children As Young As 8

FRIDAY, April 6, 2018 (HealthDay News) -- Increased adiposity in childhood may negatively impact liver function in children as young as 8 years old, according to a study published online April 4 in The Journal of Pediatrics.

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Online Doc Reviews Don't Reflect Patient Satisfaction Surveys

THURSDAY, April 5, 2018 (HealthDay News) -- Online physician reviews do not reflect patient satisfaction surveys (PSSs), according to a study published in the April issue of the Mayo Clinic Proceedings.

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ACA Marketplaces Expand Coverage for Chronically Ill

THURSDAY, April 5, 2018 (HealthDay News) -- The Affordable Care Act's Marketplaces covered a disproportionate share of non-elderly adults with high health care risks in the 2014 to 2015 time period, according to a study published in the April issue of Health Affairs.

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Variations Identified in Free-Text Directions in E-Prescriptions

WEDNESDAY, April 4, 2018 (HealthDay News) -- There is considerable variation in the quality of free-text patient directions (Sig) in electronic prescriptions (e-prescriptions), according to a study published online April 2 in the Journal of Managed Care & Specialty Pharmacy.

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Early Alcohol Use in Pregnancy Tied to Gastroschisis

TUESDAY, April 3, 2018 (HealthDay News) -- Alcohol consumption early in pregnancy may be a risk factor for the development of gastroschisis in neonates, according to a study published recently in the Journal of Maternal-Fetal & Neonatal Medicine.

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Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

MONDAY, April 2, 2018 (HealthDay News) -- The use of acid-suppressive medications and antibiotics during the first six months of infancy is tied to subsequent development of allergic disease, according to a study published online April 2 in JAMA Pediatrics.

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Grief Symptoms Similar in Donor vs Non-Donor Decision Families

MONDAY, April 2, 2018 (HealthDay News) -- Perceptions of the organ donation experience vary between relatives who decide to donate their relative's organs and those who do not, but the decision does not appear to be associated with subsequent grief symptoms, according to a study published online March 19 in the American Journal of Respiratory and Critical Care Medicine.

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