April 2015 Briefing - Diabetes & Endocrinology

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Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for April 2015. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Metabolic 'Map' May One Day Help Predict Obesity Risk

THURSDAY, April 30, 2015 (HealthDay News) -- Researchers say they have successfully linked certain byproducts of digestion to the risk of excess body fat. The findings were published in the April 29 issue of Science Translational Medicine.

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Intensive T1DM Control Greatly Lowers Odds of Ocular Surgery

THURSDAY, April 30, 2015 (HealthDay News) -- Intensive management of type 1 diabetes can reduce the risk of having a diabetes-related ocular surgery by nearly 50 percent, according to a new report. Results of the study were published in the April 30 issue of the New England Journal of Medicine.

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Long-Term Post-CABG Mortality Increased With Diabetes

WEDNESDAY, April 29, 2015 (HealthDay News) -- Patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) have increased long-term risk of death after coronary artery bypass grafting (CABG), with higher risk among those with T1DM, according to a study published in the April 28 issue of the Journal of the American College of Cardiology.

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Physician Compensation Up for Most Specialties

TUESDAY, April 28, 2015 (HealthDay News) -- Physician compensation has gone up for almost all specialties, according to a 2015 report published by Medscape.

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CDC: Surveillance System Can Help Reduce Health Care Injuries

TUESDAY, April 28, 2015 (HealthDay News) -- A surveillance system for health care facilities can be used to identify and help reduce the number of preventable injuries among health care personnel, according to research published in the April 24 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Lasting Mortality Risk Increase With Hyperglycemic Crises

TUESDAY, April 28, 2015 (HealthDay News) -- During the first six years of follow-up, geriatric patients with diabetes have a higher mortality risk after hyperglycemic crisis episode (HCE), according to a study published in the May issue of Diabetes Care.

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Benefits of Moderate Drinking Differ According to Race

MONDAY, April 27, 2015 (HealthDay News) -- Moderate drinking appears to offer greater health benefits to whites than to blacks, according to a study published online April 23 in the American Journal of Public Health.

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Hemoglobin Glycation Index IDs Harms, Benefits of T2DM Tx

MONDAY, April 27, 2015 (HealthDay News) -- The effect of intensive versus standard type 2 diabetes treatment varies according to the hemoglobin glycation index (HGI: observed hemoglobin A1c [HbA1c] − predicted HbA1c), according to a study published online April 17 in Diabetes Care.

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Focus on Calories Versus Quality of Food Misdirected

FRIDAY, April 24, 2015 (HealthDay News) -- All calories are not created equal and some foods are not as bad for weight management as many believe, according to new research published online April 8 in the American Journal of Clinical Nutrition.

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Exercise Can't Fix the Damage of a Bad Diet

FRIDAY, April 24, 2015 (HealthDay News) -- Although physical activity is important for health, a healthy diet is essential for weight loss -- and regular exercise will not make up for a poor diet, according to an editorial published online April 22 in the British Journal of Sports Medicine.

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One in 10 AMI Patients Have Unrecognized Incident Diabetes

THURSDAY, April 23, 2015 (HealthDay News) -- One in 10 acute myocardial infarction (AMI) patients without a previous diagnosis of diabetes mellitus (DM) have underlying DM, according to research published online April 21 in Circulation: Cardiovascular Quality and Outcomes.

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Abridged Standards of Care for Diabetes Developed for PCPs

THURSDAY, April 23, 2015 (HealthDay News) -- An abridged version of the 2015 Standards of Medical Care in Diabetes has been produced for primary care physicians. The condensed guidelines were published in the April issue of Clinical Diabetes.

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Concomitant Metformin, GERD Meds Up Vitamin B12 Depletion

THURSDAY, April 23, 2015 (HealthDay News) -- Concomitant use of metformin and histamine H2-receptor antagonists or proton pump inhibitors has the potential to induce vitamin B12 depletion and neuropathy, according to research published in the April issue of Clinical Diabetes.

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Increasing Number of Children Present With DKA in T1DM

WEDNESDAY, April 22, 2015 (HealthDay News) -- A growing number of American children and teens with type 1 diabetes are experiencing diabetic ketoacidosis (DKA) at the time of their diagnosis, according to research published in the April 21 issue of the Journal of the American Medical Association, a theme issue on child health.

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EHR Data Mining Helps With Quality Improvement

WEDNESDAY, April 22, 2015 (HealthDay News) -- Electronic health records (EHRs) are a valuable source of data that can be mined to help practices with quality improvement performance, according to a study published in Medical Economics.

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Sucrose Intake Linked to Higher Activity in Left Hippocampus

WEDNESDAY, April 22, 2015 (HealthDay News) -- Sucrose, but not aspartame, consumption is associated with higher activity in the left hippocampus and reduced stress-induced cortisol, according to a study published online April 16 in the Journal of Clinical Endocrinology & Metabolism.

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Eating Disorders Common in Girls With Type 1 Diabetes

WEDNESDAY, April 22, 2015 (HealthDay News) -- For girls and young women with type 1 diabetes, eating disorders are common and persistent, according to a study published online April 17 in Diabetes Care.

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High-Dose Oral Insulin Promising for Prevention of T1DM

WEDNESDAY, April 22, 2015 (HealthDay News) -- In a small, preliminary study, high-dose insulin capsules safely induced what appears to be a protective immune response in children at high risk of developing type 1 diabetes. The study findings were published in the April 21 issue of the Journal of the American Medical Association, a theme issue on child health.

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Additive Effect for Calorie Limit, Exercise on Glucoregulation

TUESDAY, April 21, 2015 (HealthDay News) -- Calorie restriction (CR) and exercise (EX)-induced weight loss have additive benefits on glucoregulation, according to a study published online April 15 in Diabetes Care.

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Guidance Offered for Managing Conflict With Patients

MONDAY, April 20, 2015 (HealthDay News) -- Good communication is key to managing conflict with patients, according to an article published April 1 in Medical Economics.

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Suboptimal Prescribing Attitudes Could Signal Personal Distress

FRIDAY, April 17, 2015 (HealthDay News) -- Medical students in personal distress may be more likely to have suboptimal attitudes about self-prescribing and personal responsibility for reporting impaired colleagues, according to a study published in the April issue of Academic Medicine.

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Apple HealthKit App Facilitates Doctor-Patient Communication

THURSDAY, April 16, 2015 (HealthDay News) -- The latest version of Apple's operating system iOS 8 allows physicians to connect with patients in many ways using the HealthKit app that collects user health and fitness data, according to an article published in Medical Economics.

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Medicare Spending Down in Year One of Pioneer ACO

THURSDAY, April 16, 2015 (HealthDay News) -- Medicare spending is down in year one of the Pioneer accountable care organization (ACO) program, according to a study published online April 15 in the New England Journal of Medicine.

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Fish Oil Supplementation Tied to Lower Atherothrombotic Risk

THURSDAY, April 16, 2015 (HealthDay News) -- Fish oil supplementation (FOS) is associated with atherothrombotic risk reduction in suspected coronary artery disease (sCAD), according to a study published in the May 1 issue of The American Journal of Cardiology.

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Prolonged ADT Ups Diabetes, CVD Risk for Older Men

THURSDAY, April 16, 2015 (HealthDay News) -- For men diagnosed with prostate cancer aged older than 70 years, prolonged androgen deprivation therapy is associated with increased risk of diabetes and cardiovascular disease, especially among those with comorbidities, according to a study published in the April issue of The Journal of Urology.

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Ethical Implications for Looking Up Applicants on Facebook

THURSDAY, April 16, 2015 (HealthDay News) -- Looking up students on Facebook and other social networking sites (SNS) is associated with ethical concerns, according to a perspective piece published in the March issue of the Journal of Graduate Medical Education.

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AMA Announces End of Sustainable Growth Rate Formula

WEDNESDAY, April 15, 2015 (HealthDay News) -- Recently adopted legislation has repealed the sustainable growth rate (SGR) formula, according to a report published by the American Medical Association (AMA).

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Depression, Diabetes Both Tied to Increased Dementia Risk

WEDNESDAY, April 15, 2015 (HealthDay News) -- Depression and diabetes both appear to significantly raise the risk of dementia, according to new research. The findings were published online April 15 in JAMA Psychiatry.

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Survey Looks at Patient Attitudes Regarding Informed Consent

WEDNESDAY, April 15, 2015 (HealthDay News) -- Most U.S. adults would prefer to be asked for permission to participate in studies assessing usual medical practices, according to a study published online April 14 in the Annals of Internal Medicine.

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Gestational Diabetes May Increase Risk of Autism

TUESDAY, April 14, 2015 (HealthDay News) -- Gestational diabetes may increase the risk a child will develop autism, according to research published in the April 14 issue of the Journal of the American Medical Association.

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Security Breaches of Health Records Up Over Past Decade

TUESDAY, April 14, 2015 (HealthDay News) -- Breaches in data security exposed more than 29 million health records to potential criminal misuse between 2010 and 2013, according to a new study. Security breaches involving hacking have nearly doubled in recent years, rising to 8.7 percent in 2013 compared with 4.7 percent in 2010, according to the study, published as a research letter in the April 14 issue of the Journal of the American Medical Association.

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Placebo Response May Depend on Individual DNA

TUESDAY, April 14, 2015 (HealthDay News) -- The strength of the placebo effect may depend on particular DNA, according to a report published online April 13 in Trends in Molecular Medicine.

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Effects of n-3 PUFAs on Insulin Sensitivity Unclear

TUESDAY, April 14, 2015 (HealthDay News) -- Dietary n-3 polyunsaturated fatty acids (PUFAs), including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), do not appear to have clinically meaningful effects on peripheral or hepatic insulin sensitivity in insulin-resistant adults without diabetes, according to research published online April 7 in Diabetes Care.

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USPSTF Review: T2DM Screening Doesn't Cut Mortality

TUESDAY, April 14, 2015 (HealthDay News) -- Type 2 diabetes screening is not associated with improved mortality rates after 10 years of follow-up, according to a U.S. Preventive Services Task Force (USPSTF) review published online April 14 in the Annals of Internal Medicine.

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Grape Polyphenols May Protect Against Metabolic Sx Via Gut

TUESDAY, April 14, 2015 (HealthDay News) -- Grape polyphenols (GP) may act in the intestine to protect against metabolic syndrome, according to an experimental study published online April 6 in Diabetes.

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SHBG Predicts Erectile Dysfunction Risk in Young Men

TUESDAY, April 14, 2015 (HealthDay News) -- High levels of free testosterone (FT) and bioavailable testosterone (BT), and low levels of sex hormone-binding globulin (SHBG), are tied to a decreased risk of erectile dysfunction (ED) in young men, according to a study published online March 20 in the Journal of Sexual Medicine.

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Exercise Cuts Pain Interference From Diabetic Neuropathy

MONDAY, April 13, 2015 (HealthDay News) -- Aerobic exercise may help reduce perceived pain interference resulting from diabetic peripheral neuropathy (DPN), according to a brief research report published online March 20 in Pain Medicine.

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Study Highlights Third-Line Treatment Options for T2DM

MONDAY, April 13, 2015 (HealthDay News) -- Treatment escalation options have different efficacy following failure of exenatide or glimepiride added to metformin in patients with type 2 diabetes mellitus, according to a study published online April 1 in Diabetes, Obesity and Metabolism.

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Medical Debt Burden Higher in Texas, Florida

FRIDAY, April 10, 2015 (HealthDay News) -- Significantly more adults in Florida and Texas struggle to pay medical bills or pay off medical debt over time compared with residents of New York and California, according to a new Commonwealth Fund report released Friday.

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Many Doctors Haven't Started Dealing With ICD-10 Revision

FRIDAY, April 10, 2015 (HealthDay News) -- Most physicians have barely begun to deal with issues relating to documentation associated with the transition to the International Classification of Diseases, 10th Revision (ICD-10), according to an article published in Medical Economics.

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Art Program Hones Med Students' Visual Observation Skills

FRIDAY, April 10, 2015 (HealthDay News) -- An innovative interdisciplinary program, Art Rounds, is effective for improving medical and nursing students' physical observation skills, according to a study published in the April issue of the Journal of Nursing Education.

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Exercise Dose, Intensity Don't Impact Reduction in Liver Fat

FRIDAY, April 10, 2015 (HealthDay News) -- Reductions in liver fat or visceral adipose tissue (VAT) do not differ significantly with the dose or intensity of aerobic exercise, according to a study published online April 8 in the Journal of Hepatology.

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Overweight/Obesity Linked to Reduced Risk of Dementia

FRIDAY, April 10, 2015 (HealthDay News) -- A new study of nearly two million people suggests that those who are overweight or obese in middle age may be less likely to develop dementia than their normal-weight and underweight peers. The report was published online April 9 in The Lancet Diabetes & Endocrinology.

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Candy Twists Alternative to Glucola Drink for GDM Screening

THURSDAY, April 9, 2015 (HealthDay News) -- Candy twists can be used as an alternative to glucola beverage in gestational diabetes mellitus screening, according to a study published in the April issue of the American Journal of Obstetrics & Gynecology.

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Pharmacists Raise Concerns for Patient Access to Generic Drugs

THURSDAY, April 9, 2015 (HealthDay News) -- Nearly all pharmacists have experienced upswings in the acquisition costs of generic drugs, with price spikes reported to be worse since 2013, according to a report published by the National Community Pharmacists Association (NCPA).

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Additional Attention to Modifiable Risks in DM Could Benefit Greatly

WEDNESDAY, April 8, 2015 (HealthDay News) -- For adults with diabetes, inadequately controlled risk factors account for a considerable proportion of cardiovascular events and death, according to a study published online in Diabetes Care.

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Limited Time Available to Review Sunshine Act Data

WEDNESDAY, April 8, 2015 (HealthDay News) -- Physicians have only 45 days to review and dispute reports regarding their financial ties to drug and medical device manufacturers reported under the Physician Payments Sunshine Act, according to the American Medical Association (AMA).

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Med Students, Residents Rarely Perform Stethoscope Hygiene

TUESDAY, April 7, 2015 (HealthDay News) -- Stethoscope hygiene is rarely performed by trainee physicians, according to a research letter published online April 2 in the Journal of Hospital Medicine.

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Success Seen With Mini-Group Visits for Patients With Diabetes

TUESDAY, April 7, 2015 (HealthDay News) -- Mini-group visits yield good results among patients with diabetes, according to a report published by the American Academy of Family Physicians.

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Two Commercial Weight Loss Plans Come Out on Top

TUESDAY, April 7, 2015 (HealthDay News) -- Only two out of 32 major commercial weight-loss programs marketed nationwide -- Weight Watchers and Jenny Craig -- can boast scientific evidence showing their clients maintain weight loss for at least a year, according to a new study published in the April 7 issue of the Annals of Internal Medicine.

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Semen Quality Linked to Fruit, Veggie Pesticide Residue

TUESDAY, April 7, 2015 (HealthDay News) -- High-pesticide residue fruit and vegetable intake correlates with poorer semen quality, according to a study published online March 30 in Human Reproduction.

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Hx of Depression Tied to Higher Risk of Gestational Diabetes

TUESDAY, April 7, 2015 (HealthDay News) -- Women with gestational diabetes mellitus (GDM) are more likely to have a history of depression, according to a study published in the March/April issue of the Journal of Obstetric, Gynecologic, & Neonatal Nursing.

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DPP-4 Inhibitors Not Tied to Pneumonia Hospitalizations

MONDAY, April 6, 2015 (HealthDay News) -- The use of dipeptidyl peptidase-4 (DPP-4) inhibitors is not associated with an increased risk of hospitalization for community-acquired pneumonia, according to a study published in the April issue of Diabetes, Obesity and Metabolism.

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Lifestyle Interventions for Diabetes Yield Modest Results

MONDAY, April 6, 2015 (HealthDay News) -- Lifestyle-based weight loss intervention trials in type 2 diabetes achieve modest reductions in weight and glycated hemoglobin (HbA1c) levels, according to a meta-analysis published in the April issue of Diabetes, Obesity and Metabolism.

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Article Highlights Legal Issues Linked to Physician Extenders

FRIDAY, April 3, 2015 (HealthDay News) -- The use of physician extenders (PEs; mainly physician assistants and nurse practitioners) may bring added legal risks to a practice, according to an article published in Medical Economics.

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Sodium Content Too High in Over Half of Packaged Foods

FRIDAY, April 3, 2015 (HealthDay News) -- More than half of packaged grocery store foods included in a new study contained too much added salt, U.S. health officials reported Thursday. The report was published April 2 in the U.S. Centers for Disease Control and Prevention's Preventing Chronic Disease.

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Botulinum Toxin-A Beneficial in Painful Diabetic Neuropathy

FRIDAY, April 3, 2015 (HealthDay News) -- Botulinum toxin-A (BTX-A) appears to be beneficial for painful diabetic neuropathy (PDN), according to a meta-analysis published online March 20 in Pain Medicine.

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Patients May Be Modifying Meds Due to Trouble Swallowing

THURSDAY, April 2, 2015 (HealthDay News) -- Some patients experience difficulties swallowing and modify medication dosage forms, without necessarily consulting health professionals, according to research published in the March issue of the Journal of Pharmacy Practice and Research.

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Moderate Alcohol Consumption May Cut Fasting Insulin, HbA1c

WEDNESDAY, April 1, 2015 (HealthDay News) -- Among individuals without diabetes, moderate alcohol consumption may decrease fasting insulin and hemoglobin A1c (HbA1c) concentrations, according to a review and meta-analysis published in the April issue of Diabetes Care.

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Legal Issues of Removing Patient From Practice Explored

WEDNESDAY, April 1, 2015 (HealthDay News) -- The legal and ethical responsibilities of removing a patient from practice are discussed in an article published March 16 in Medical Economics.

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Serious Adverse Drug Reactions Still Occur With Bromocriptine

WEDNESDAY, April 1, 2015 (HealthDay News) -- Serious adverse drug reactions (ADRs) can occur after bromocriptine use in lactation inhibition, most of which could be avoided, according to a study published online March 11 in BJOG: An International Journal of Obstetrics & Gynecology.

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Metformin Use Associated With Less CRC Risk in U.S. Population

WEDNESDAY, April 1, 2015 (HealthDay News) -- For patients with diabetes in the United States, metformin use is associated with reduced risk of developing colorectal cancer (CRC), according to a study published in the April 1 issue of Cancer.

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