Approach Offers Regional Control of HPV-Related Head, Neck CA

This article originally appeared here.
Share this content:
Approach Offers Regional Control of HPV-Related Head, Neck CA
Approach Offers Regional Control of HPV-Related Head, Neck CA

FRIDAY, Feb. 9, 2018 (HealthDay News) -- Good regional control can be achieved with up-front surgery and adjuvant therapy for patients with invasive nodal disease from oropharyngeal squamous cell carcinoma (SCC) related to human papillomavirus (HPV), according to a study published online Jan. 29 in Head & Neck.

Joseph Zenga, M.D., from Washington University in Saint Louis, and colleagues assessed oncologic outcomes among 72 patients with HPV-related oropharyngeal SCC requiring resection of major muscular or neurovascular tissue during neck dissection for invasive nodal disease.

The researchers found that regional recurrences were seen in 6 percent of patients, and 17 percent experienced distant recurrences. Decreased disease-free survival was associated with advanced T classification, pathological node number ≥5, and omission of adjuvant therapy. However, adding adjuvant chemotherapy did not improve survival.

"In patients with HPV-related oropharyngeal SCC requiring resection of major muscular or neurovascular tissue due to invasive nodal disease, up-front surgical management with adjuvant therapy results in excellent long-term regional control," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »