Antireflux Surgery Has High Rate of Recurrent Disease

Share this content:
Antireflux Surgery Has High Rate of Recurrent Disease
Antireflux Surgery Has High Rate of Recurrent Disease

WEDNESDAY, Sept. 13, 2017 (HealthDay News) -- Laparoscopic antireflux surgery is associated with a relatively high rate of recurrent gastroesophageal reflux disease, according to a study published in the Sept. 12 issue of the Journal of the American Medical Association.

John Maret-Ouda, M.D., from the Karolinska University Hospital in Stockholm, and colleagues analyzed data from the Swedish Patient Registry to identify 2,655 patients who underwent laparoscopic antireflux surgery. Records were linked to the Swedish Causes of Death Registry and Prescribed Drug Registry.

The researchers found that over a median of 5.6 years, 17.7 percent of patients had reflux recurrence, 83.6 percent received long-term antireflux medication, and 16.4 percent underwent secondary antireflux surgery. Female sex (hazard ratio [HR], 1.57; 95 percent confidence interval [CI], 1.29 to 1.90), older age (HR, 1.41; 95 percent CI, 1.10 to 1.81), and comorbidity (HR, 1.36; 95 percent CI, 1.13 to 1.65) were risk factors for reflux recurrence. Recurrence risk was not tied to hospital volume of antireflux surgery (HR, 1.09 [95 percent CI, 0.77 to 1.53] for hospital volume ≤24 surgeries versus hospitals with ≥76 surgeries).

"Laparoscopic antireflux surgery was associated with a relatively high rate of recurrent gastroesophageal reflux disease requiring treatment, diminishing some of the benefits of the operation," the authors write.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Ground Beef Recalled After E. Coli Outbreak

Ground Beef Recalled After <i>E. Coli</i> Outbreak

Beef was produced and packaged at Cargill Meat Solutions in Fort Morgan, Colo.

Prevalence of Alzheimer's, Related Dementia Set to Double

Prevalence of Alzheimer's, Related Dementia Set to Double

Alzheimer's disease and related dementias burden is expected to increase to 3.3 percent in 2060

Long-Term Outcomes of Breast Implants Explored

Long-Term Outcomes of Breast Implants Explored

Higher rates of Sjogren syndrome, scleroderma, RA, stillbirth, melanoma for silicone implants

is free, fast, and customized just for you!




Already a member?

Sign In Now »