Anticoagulation Guidance Issued for Cardiopulmonary Bypass

Share this content:
Anticoagulation Guidance Issued for Cardiopulmonary Bypass
Anticoagulation Guidance Issued for Cardiopulmonary Bypass

MONDAY, Jan. 22, 2018 (HealthDay News) -- Clinical practice guidelines for anticoagulation therapy for cardiopulmonary bypass (CPB) have been developed and were published in the February issue of the Annals of Thoracic Surgery.

Noting that the evidence base relating to anticoagulation therapy for CPB has not been organized into a succinct guideline and that considerable practice variability exists, Linda Shore-Lesserson, M.D., from the Zucker School of Medicine at Hofstra Northwell in Hampstead, N.Y., and colleagues conducted a systematic literature review to establish best practices in anticoagulation therapy for CPB. Data from 96 manuscripts were reviewed, and 17 manuscripts, considered sentinel publications and published before 2000, were included to provide method, context, or additional supporting evidence.

The researchers developed recommendations based on review of the articles; for each recommendation they achieved more than two-thirds agreement. Recommendations were written in three areas: heparin dosing and monitoring for CPB initiation and maintenance; contraindications and alternatives to heparin; and anticoagulation reversal during cardiac procedures.

"It is hoped that this guideline will serve as a resource and will stimulate investigators to conduct more research and to expand on the evidence base on the topic of anticoagulation therapy for CPB," the authors write.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: First U.S. Case of Rat-Borne Andes Virus Diagnosed

CDC: First U.S. Case of Rat-Borne Andes Virus ...

New World hantavirus can present with symptoms similar to those of the flu

Variability in Geographic Availability of New Antibiotics

Variability in Geographic Availability of New Antibiotics

Greater geographic availability for antibiotics from and/or marketed by companies in U.S., Europe

CDC: Vaccination Rates More Than 95 Percent for Kindergartners

CDC: Vaccination Rates More Than 95 Percent for ...

Coverage could be even higher if schools followed up with under-vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »