Altered Neural Responses in Memory Processing in T1DM

Share this content:
Altered Neural Responses in Memory Processing in T1DM
Altered Neural Responses in Memory Processing in T1DM

MONDAY, March 19, 2018 (HealthDay News) -- Young adults with type 1 diabetes have altered neural responses during working memory processing, according to a study published online March 12 in Diabetes.

Christine M. Embury, from the University of Nebraska Medical Center in Omaha, and colleagues examined the correlation between diabetes and cognitive impairment in a cohort of young adults with and without type 1 diabetes who were virtually free of comorbidities that have been independently linked to cognitive deficits (such as obesity and hypertension). Participants completed a verbal working memory task during magnetoencephalographic brain imaging.

The researchers found that, compared with controls, patients had significantly stronger neural responses in the superior parietal cortices during memory encoding, while during maintenance, activity was significantly weaker in parietal-occipital regions. There were significant correlations for disease duration and glycemic control with neural responses in various brain regions.

"Young healthy adults with type 1 diabetes already have aberrant neural processing relative to their nondiabetic peers, employing compensatory responses to perform the task, and glucose management and duration may play a central role," the authors write.

One author disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Approves First Customizable Insulin Pump

FDA Approves First Customizable Insulin Pump

Product works by delivering insulin under the skin at set or variable rates

Sepsis Common in Terminal Hospitalizations, Discharges

Sepsis Common in Terminal Hospitalizations, Discharges

Most common underlying causes of death in sepsis are solid and hematologic cancers, chronic heart disease

Fewer Older Men Assessed, Treated for Osteoporosis

Fewer Older Men Assessed, Treated for Osteoporosis

Fewer older men than women, even with higher risk, undergo DXA screening, 25(OH)D measurement

is free, fast, and customized just for you!




Already a member?

Sign In Now »