Adding Daratumumab to Standard Tx Effective in Multiple Myeloma

Share this content:
Adding Daratumumab to Standard Tx Effective in Multiple Myeloma
Adding Daratumumab to Standard Tx Effective in Multiple Myeloma

FRIDAY, Oct. 7, 2016 (HealthDay News) -- Adding daratumumab to standard treatment for advanced cases of multiple myeloma may significantly improve patients' chances of a response and even recovery, according to a study published in the Oct. 6 issue of the New England Journal of Medicine.

Meletios Dimopoulos, M.D., a professor at the National and Kapodistrian University of Athens in Greece, and colleagues recruited 569 myeloma patients and randomly assigned them to receive either lenalidomide and dexamethasone alone (standard treatment) or with the addition of daratumumab (three-drug regimen).

Over a median follow-up of 13.5 months, the researchers found that 41.0 percent of the patients in the standard-treatment group either died or saw their cancer progress. That compared with only 18.5 percent of patients receiving the three-drug regimen. Use of daratumumab was associated with more than doubling the rate of complete response: 43.1 percent, versus 19.2 percent.

"It is very likely that (this regimen) will be rapidly adopted by practicing physicians," Dimopoulos told HealthDay.

Janssen Biotech, which markets daratumumab, funded the study. Dimopoulos and some of the co-researchers have served on the company's advisory board.

Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »