ACS: Accepting Liver From Older Donor Better Than Waiting

This article originally appeared here.
Share this content:
ACS: Accepting Liver From Older Donor Better Than Waiting
ACS: Accepting Liver From Older Donor Better Than Waiting

TUESDAY, Oct. 23, 2018 (HealthDay News) -- Accepting a liver from an older liver donor (OLD) is associated with long-term survival benefit, according to a study presented at the annual meeting of the American College of Surgeons, held from Oct. 21 to 25 in Boston.

Christine E. Haugen, M.D., from the Johns Hopkins University in Baltimore, and colleagues identified 42,533 adult liver transplantation candidates offered OLDs that were eventually transplanted in another recipient. Patients were followed from date of offer until death or the end of the study.

The researchers found that 48.8 percent of candidates who declined an OLD had died or were removed from the waitlist after five years. Compared with candidates who declined OLDs, the risk for mortality was lower for candidates who accepted OLDs within 90 days post-decision (adjusted hazard ratio, 0.61) and beyond 90 days post-decision (adjusted hazard ratio, 0.39). OLD acceptance correlated with a decreased risk for mortality beyond 90 days for candidates with a Model for End-Stage Liver Disease (MELD) score of 10 to 24 or 25 to 34 (adjusted hazard ratios, 0.44 and 0.46, respectively). OLD acceptance also correlated with a reduced risk for mortality within the first 90 days for candidates with a MELD score of 35 to 40 (adjusted hazard ratio, 0.22).

"In our study, we demonstrate that if you get an offer from an older donor, you should probably consider accepting the organ, because there is now a demonstrated survival benefit in doing so," Haugen said in a statement.

Abstract
More Information

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

CDC: Progress in HIV Prevention Has Stalled in the United States

CDC: Progress in HIV Prevention Has Stalled in ...

Agency says effective HIV prevention, treatment not reaching those who could most benefit

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children

AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in ...

All children with sustained unresponsiveness ingested concentrated and baked egg

Prenatal Vitamin Intake in Early Pregnancy May Cut Autism Risk

Prenatal Vitamin Intake in Early Pregnancy May Cut ...

ASD risk down for children whose mothers took prenatal vitamins during first month of pregnancy

is free, fast, and customized just for you!




Already a member?

Sign In Now »