AAN: SUDEP Incidence 1 in 4,500 Children, 1 in 1,000 Adults/Year

This article originally appeared here.
Share this content:
AAN: SUDEP Incidence 1 in 4,500 Children, 1 in 1,000 Adults/Year
AAN: SUDEP Incidence 1 in 4,500 Children, 1 in 1,000 Adults/Year

TUESDAY, April 25, 2017 (HealthDay News) -- The incidence of sudden unexpected death in epilepsy (SUDEP) is 0.22 per 1,000 patient-years for children and 1.2 per 1,000 patient-years for adults, according to a new guideline published online April 24 in Neurology to coincide with the annual meeting of the American Academy of Neurology, held from April 22 to 28 in Boston.

Cynthia Harden, M.D., from Mount Sinai Health System in New York City, and colleagues conducted a systematic review of the evidence to determine the incidence rates of SUDEP in different epilepsy populations and assess risk factors for SUDEP.

The researchers found that based on 12 Class I studies, SUDEP risk in children with epilepsy was 0.22 per 1,000 patient-years. The risk increased to 1.2 per 1,000 patient-years in adults. The major risk factor for SUDEP was generalized tonic-clonic seizures (GTCS); the risk of SUDEP increased with increasing frequency of GTCS occurrence. Based on these results, the researchers recommend that clinicians should inform parents and guardians that SUDEP typically affects one in 4,500 children per year. Clinicians should inform adult patients that SUDEP typically affects one in 1,000 adults per year.

"It is important that the rate of occurrence of SUDEP and the specific risk factors for SUDEP are communicated to persons and families affected by epilepsy," Harden said in a statement. "Our guideline brings clarity to the discussion, giving health care providers practical information they can use to help people with epilepsy reduce their risk."

Several authors disclosed financial ties to pharmaceutical companies.

Abstract
Full Text
More Information

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Trending Activities

All Professions

Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Permits Marketing of Brain Stimulation Device for OCD

FDA Permits Marketing of Brain Stimulation Device for ...

FDA previously approved transcranial magnetic stimulation for major depression, certain migraines

Comments Open on End of NIH Review for Gene Therapy Studies

Comments Open on End of NIH Review for ...

NIH oversight panel no longer plans to review all applications for gene therapy experiments

U.S. Measles Outbreak Hits 107 Cases in 21 States, D.C.

U.S. Measles Outbreak Hits 107 Cases in 21 ...

Outbreak on track to exceed last year's; most of the people who got measles weren't vaccinated

is free, fast, and customized just for you!




Already a member?

Sign In Now »