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Getting It Right: Applying Guideline-Directed Medical Therapy in Chronic Heart Failure

Getting It Right: Applying Guideline-Directed Medical Therapy in Chronic Heart Failure


Expert Perspective

Time to Complete

1.25 hours


January 18, 2019


January 18, 2020
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Maximum Credits

1.25 / AMA PRA Category 1 CreditsTM

Accredited Provider

Provided by Haymarket Medical Education

Commercial Supporter

Supported by an educational grant from Novartis Pharmaceuticals Corporation

Program Description

Despite multiple evidence-based expert guidelines for the management of chronic heart failure (HF)—as well as meaningful improvements in patient survival in recent years—clinicians remain challenged about how best to care for this complex population. Thus, significant gaps remain in clinicians’ adherence to treatment recommendations in HF, including underuse and/or inadequate dose titration of guideline-directed medical therapies (GDMTs).

Recent data from the CHAMP-HF (Change the Management of Patients With Heart Failure) registry show that among patients eligible for all classes of HF medication, only 1% simultaneously receive target doses of an angiotensin-converting enzyme inhibitor (ACEI)/angiotensin II receptor blocker (ARB), angiotensin receptor-neprilysin inhibitor (ARNI), beta-blocker, and mineralocorticoid receptor antagonist (MRA).1

In this enduring myCME TOWN WALLTM presentation, the expert faculty will address some of the most vexing problems clinicians face in providing optimal medical therapy for patients with HF, including:

  • Best practices in risk assessment and stratification
  • Selecting medications based on pathophysiologic targets and comorbidities
  • Uptitrating indicated agents to evidence-based target doses
  • Leveraging the multidisciplinary care team to achieve optimal outcomes, especially during transitions in care

1. Greene SJ, Butler J, Albert NM, et al. Medical therapy for heart failure with reduced ejection fraction: the CHAMP-HF Registry. J Am Coll Cardiol. 2018;72:351-366.

Intended Audience

This activity is designed for cardiologists, internists, and other clinicians who care for patients with chronic HF, including primary care physicians (ie, family medicine/general practice), nurse practitioners, and physician assistants.

Educational Objectives

At the conclusion of this activity, participants should be better able to:

  • Assess patients’ global clinical status, including prompt recognition of worsening HF
  • Apply evidence-based GDMT when managing patients with chronic HF, including uptitration of medication to recommended target levels
  • Identify candidates for newer HF agents (eg, sacubitril/valsartan, ivabradine)
  • Collaborate effectively with the multidisciplinary care team, including the patient and caregiver, especially during transitions in care

Conflict Of Interest Disclosure Policy

In accordance with the ACCME Standards for Commercial Support, Haymarket Medical Education requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. Haymarket Medical Education resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational activities.


Peter Salgo, MD

Professor of Medicine and Anesthesiology
Columbia University College of Physicians and Surgeons
Associate Director of Surgical Intensive Care
Columbia University Medical Center
New York, NY

Dr. Salgo has no relevant financial relationships to disclose.

Alison L. Bailey, MD, FACC, FAACVPR

Program Director, Cardiovascular Diseases Fellowship
Director, Preventive Cardiology and Cardiac Rehabilitation Program
Erlanger Heart and Lung Institute
University of Tennessee College of Medicine - Chattanooga
Chattanooga, TN

Dr. Bailey was the lead investigator for clinical trials that received funding from Theracos, Inc., and ZOLL.

Peter S. Pang, MD, MS, FAHA, FACC, FACEP
Associate Professor
Department of Emergency Medicine
Indiana University School of Medicine
Indianapolis, IN

Dr. Pang receives consulting fees from Bristol-Myers Squibb, Novartis Pharmaceuticals Corporation, Roche Diagnostics, and Trevena and receives research grants from the American Heart Association, National Institutes of Health, Novartis Pharmaceuticals Corporation, Patient-Centered Outcomes Research Institute, and Roche Diagnostics.

Clinical Professor of Medicine
University of Illinois at Chicago
Chicago, IL

Dr. Silver has no relevant financial relationships to disclose.

Ginger Biesbrock, PA-C, MPH, MPAS, AACC

Vice President, MedAxiom Consulting
Grand Rapids, MI

Ms. Biesbrock has no relevant financial relationships to disclose.

Robin E. Traufler, MN, APRN-BC, ACNP, CHFN
Advanced Heart Health Center
Palmetto Health Richland
Columbia, SC

Ms. Traufler receives consulting fees from Abbott and is on the speaker’s bureau of ZOLL.

Accredited Provider Disclosures

Haymarket Medical Education staff involved in the planning and content review of this activity have no relevant financial relationships to disclose.




AMA PRA Category 1 Credit(s)TM

Accreditation Statement

Haymarket Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation Statement

Haymarket Medical Education designates this enduring material for a maximum of 1.25 AMA PRA Category 1 CreditsTM  .  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Additional Credit Information

Physician Assistant Continuing Education
AAPA accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM   from organizations accredited by ACCME or a recognized state medical society. PAs may receive a maximum of 1.25 Category 1 Credits for completing this activity.

Nurse Practitioner Continuing Education
AANPCP accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM   from organizations accredited by ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.

Disclosure of Unlabeled Use

This CME activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.


The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Novartis Pharmaceuticals Corporation or Haymarket Medical Education. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

If you have any questions relating to the accreditation of this activity, please contact Julie A. Tagliareni at

If you have any other questions relating to your certificate or other issues with the activity, please contact


To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

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