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Comprehensive Genomic Profiling: Towards Precision Medicine

Comprehensive Genomic Profiling: Towards Precision Medicine


Slide Lecture Series

Time to Complete

1 hour


May 13, 2019


May 13, 2020
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Maximum Credits

1.00 / AMA PRA Category 1 Credit(s)TM

Accredited Provider

This activity is provided by EXCEL Continuing Education.

Commercial Supporter

This activity is supported by an educational grant from ILLUMINA.

Program Description

Our understanding of cancer genomics is dramatically changing cancer diagnostics, leading the way to personalized cancer care. Delivering comprehensive genomic profiling for clinical cancer care is transforming cancer care. Therapy targeting the alterations that drive an individual patient’s cancer can yield dramatic results. When correctly implemented, next generation sequencing (NGS) methods provide millions of individual observations that are representative of the genetic makeup of a sample. Hybridization capture of target genomic regions allows NGS to be used for comprehensive profiling of clinical oncology specimens. This enduring activity intends to close knowledge and competence gaps regarding the use of comprehensive genomic profiling, allowing physicians to prescribe the most effective, targeted cancer treatments to patients based on the genomic information specific to their own cancer (precision medicine).

Intended Audience

Pathologists, oncologists, and other healthcare professionals who wish to improve their knowledge and understanding of comprehensive genomic profiling and its impact on clinical care.

Educational Objectives

At the conclusion of this activity, participants should be able to:

  • Describe the use of comprehensive genomic profiling to analyze clinical specimens to detect clinically relevant alterations in hundreds of cancer-related genes
  • Compare benefits and drawbacks of panel vs comprehensive genomic profiling approaches in the care of cancer patients
  • Assess the impact of false positive findings when employing tumor only assessment strategies
  • Identify why patients may benefit from comprehensive genomic profiling when determining individualized therapy

Conflict Of Interest Disclosure Policy

In accordance with the ACCME Standards for Commercial Support, EXCEL requires that individuals able to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. EXCEL resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational activities.


Theresa A. Boyle, MD, PhD, FCAP
Thoracic Molecular Pathologist
Assistant Member / Professor
Moffitt Cancer Center
University of South Florida
Tampa, FL

Dr. Boyle has received honoraria as a speaker for Illumina.

Accredited Provider Disclosure

Peer reviewer and EXCEL staff have no relevant financial information to disclose.




AMA PRA Category 1 Credit(s)TM

Accreditation Statement

EXCEL Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation Statement

EXCEL Continuing Education designates this enduring activity for a maximum of 1.00 AMA PRA Category 1 CreditsTM  . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure of Unlabeled Use

The opinions expressed in this activity are those of the individual faculty members and do not necessarily reflect those of EXCEL Continuing Education and Illumina. If products are mentioned, please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.


To obtain credit, a score of 75% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

For questions regarding this activity, please contact EXCEL Continuing Education at or phone (305) 630-9414.

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Hardware and Software Requirements
  • A computer with an internet connection
  • Internet Browser: Internet Explorer 7.x or higher, Firefox 4.x or higher, Safari 2.x or higher, or any other W3C standards compliant browser
  • Additional Software: Adobe Flash Player and/or an HTML 5 capable browser maybe required for video or audio playback. PowerPoint or Adobe Acrobat Reader may occasionally be required
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