Atopic dermatitis (AD) or atopic eczema, is a chronic, relapsing, pruritic, inflammatory skin disorder that is the most common chronic inflammatory disease. Individualized therapy for the AD patient should be implemented according to patient’s age, severity of the illness, and its extent and distribution. The intensity of management and treatment of AD is dictated directly by the severity of illness, which relates to the effect of AD on the quality of life of the patient and his or her family. This case study follows the course and management of AD in a patient throughout her life, and includes a discussion between the patient, her primary care clinician, and AD experts. The discussion includes diagnosis, management at different ages, flares, comorbid conditions, and the availability of newer therapeutic options.