0.50 / AMA PRA Category 1 CreditTM 0.50 / CNE Contact Hour
Jointly provided by Haymarket Medical Education (HME) and AKH Inc., Advancing Knowledge in Healthcare
Supported by an educational grant from Bristol-Myers Squibb
Rheumatologic immune-related adverse events (irAEs) associated with anti–PD 1 therapy have been increasingly observed in clinical practice, impacting patient adherence and quality of life while presenting new challenges to treating clinicians. When treating individuals receiving immune checkpoint inhibitor (ICI) therapies, clinicians are likely to encounter a wide variety of specific rheumatic irAEs such as inflammatory arthritis, sicca syndrome, myositis, polymyalgia rheumatica, and crystal disease. Treatment considerations are often different for irAEs compared with other rheumatic conditions.
In this educational activity—the final segment of a series of 3 interrelated myCME Go activities—a rheumatologist and an oncologist explore best practices for a patient with a history of moderate rheumatoid arthritis who is newly diagnosed with metastatic renal cell carcinoma. Considerations for the use of ICI therapy for this individual will be discussed, especially concerns for potentially worsening the patient’s arthritis. The faculty will review evidence-based recommendations for treating this patient and discuss appropriate, ongoing monitoring strategies.
Rheumatologists, rheumatology nurses, and NPs and PAs with a specialty in rheumatology
At the conclusion of this activity, participants should be better able to:
Describe the clinical and safety concerns for initiating immune checkpoint inhibitor (ICI) therapy in patients with a history of rheumatologic disease
Implement evidence-based guidelines for treating patients with cancer and preexisting rheumatologic diseases
Conflict Of Interest Disclosure Policy
In accordance with the ACCME Standards for Commercial Support, HME and AKH require that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. HME and AKH resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational activities.
Julie R. Brahmer, MD, MSc Co-Director, Upper Aerodigestive Department Bloomberg~Kimmel Institute for Cancer Immunotherapy Professor of Oncology Sidney Kimmel Cancer Center Baltimore, MD
Dr. Brahmer is a consultant for Amgen, Celgene, Genentech, Inc., Lilly, Merck & Co., Inc., and Syndax Pharmaceuticals Inc. She has received research funds from Bristol-Myers Squibb, MedImmune/AstraZeneca, and Merck & Co., Inc., and is on the advisory board of Bristol-Myers Squibb.
Laura C. Cappelli, MD, MHS Assistant Professor of Medicine Johns Hopkins Division of Rheumatology Baltimore, MD
Dr. Cappelli is a consultant for Bristol-Myers Squibb and has received royalties from Regeneron/Sanofi.
Accredited Provider Disclosure
The staff of Haymarket Medical Education and Dorothy Caputo, MA, BSN, RN, Lead Nurse Planner of AKH Inc., Advancing Knowledge in Healthcare have no relevant financial relationships to disclose.
AMA PRA Category 1 Credit(s)TM
Haymarket Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Haymarket Medical Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 CreditTM . Physicians should claim only the credit commensurate with the extent of their participation in the activity.
CNE Contact Hour(s)
AKH Inc., Advancing Knowledge in Healthcare is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.
This activity is awarded 0.50 contact hour.
Additional Credit Information
Physician Assistant Continuing Education AAPA accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM from organizations accredited by ACCME or a recognized state medical society. PAs may receive a maximum of 0.50 Category 1 Credit for completing this activity.
Nurse Practitioner Continuing Education AANPCP accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM from organizations accredited by ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.
Disclosure of Unlabeled Use
This CME/CE activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient's medical condition.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Haymarket Medical Education, AKH Inc., Advancing Knowledge in Healthcare, or Bristol-Myers Squibb. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Default instructions: To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.