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Case Clinic: Considerations for Immunotherapy in a Patient With Moderate Rheumatoid Arthritis

Case Clinic: Considerations for Immunotherapy in a Patient With Moderate Rheumatoid Arthritis

Format

Webcast

Time to Complete

30 minutes

Released

April 15, 2019

Expires

April 15, 2020
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Maximum Credits

0.50 / AMA PRA Category 1 CreditTM
0.50 / CNE Contact Hour

Accredited Provider

Jointly provided by Haymarket Medical Education (HME) and AKH Inc., Advancing Knowledge in Healthcare

Commercial Supporter

Supported by an educational grant from Bristol-Myers Squibb

Program Description

Rheumatologic immune-related adverse events (irAEs) associated with anti–PD 1 therapy have been increasingly observed in clinical practice, impacting patient adherence and quality of life while presenting new challenges to treating clinicians. When treating individuals receiving immune checkpoint inhibitor (ICI) therapies, clinicians are likely to encounter a wide variety of specific rheumatic irAEs such as inflammatory arthritis, sicca syndrome, myositis, polymyalgia rheumatica, and crystal disease. Treatment considerations are often different for irAEs compared with other rheumatic conditions.

In this educational activity—the final segment of a series of 3 interrelated myCME Go activities—a rheumatologist and an oncologist explore best practices for a patient with a history of moderate rheumatoid arthritis who is newly diagnosed with metastatic renal cell carcinoma. Considerations for the use of ICI therapy for this individual will be discussed, especially concerns for potentially worsening the patient’s arthritis. The faculty will review evidence-based recommendations for treating this patient and discuss appropriate, ongoing monitoring strategies.

Intended Audience

Rheumatologists, rheumatology nurses, and NPs and PAs with a specialty in rheumatology

Educational Objectives

At the conclusion of this activity, participants should be better able to:

  • Describe the clinical and safety concerns for initiating immune checkpoint inhibitor (ICI) therapy in patients with a history of rheumatologic disease
  • Implement evidence-based guidelines for treating patients with cancer and preexisting rheumatologic diseases

Conflict Of Interest Disclosure Policy

In accordance with the ACCME Standards for Commercial Support, HME and AKH require that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. HME and AKH resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational activities.

Faculty

Julie R. Brahmer, MD, MSc
Co-Director, Upper Aerodigestive Department
Bloomberg~Kimmel Institute for Cancer Immunotherapy
Professor of Oncology
Sidney Kimmel Cancer Center
Baltimore, MD

Dr. Brahmer is a consultant for Amgen, Celgene, Genentech, Inc., Lilly, Merck & Co., Inc., and Syndax Pharmaceuticals Inc. She has received research funds from Bristol-Myers Squibb, MedImmune/AstraZeneca, and Merck & Co., Inc., and is on the advisory board of Bristol-Myers Squibb.

Laura C. Cappelli, MD, MHS
Assistant Professor of Medicine
Johns Hopkins Division of Rheumatology
Baltimore, MD

Dr. Cappelli is a consultant for Bristol-Myers Squibb and has received royalties from Regeneron/Sanofi.

Accredited Provider Disclosure

The staff of Haymarket Medical Education and Dorothy Caputo, MA, BSN, RN, Lead Nurse Planner of AKH Inc., Advancing Knowledge in Healthcare have no relevant financial relationships to disclose.

Credit

0.50

Type

AMA PRA Category 1 Credit(s)TM

Accreditation Statement

Haymarket Medical Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation Statement

Haymarket Medical Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 CreditTM  .  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Credit

0.50

Type

CNE Contact Hour(s)

Accreditation Statement

AKH Inc., Advancing Knowledge in Healthcare is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.

Designation Statement

This activity is awarded 0.50 contact hour.

Additional Credit Information

Physician Assistant Continuing Education
AAPA accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM   from organizations accredited by ACCME or a recognized state medical society. PAs may receive a maximum of 0.50 Category 1 Credit for completing this activity.

Nurse Practitioner Continuing Education
AANPCP accepts certificates of participation for educational activities approved for AMA PRA Category 1 CreditTM   from organizations accredited by ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.

Disclosure of Unlabeled Use

This CME/CE activity may or may not discuss investigational, unapproved, or off-label use of drugs. Participants are advised to consult prescribing information for any products discussed. The information provided in this CME/CE activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient's medical condition.

Disclaimer

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Haymarket Medical Education, AKH Inc., Advancing Knowledge in Healthcare, or Bristol-Myers Squibb. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

If you have any questions relating to the CME accreditation of this activity, please contact cmequestions@haymarketmedical.com.

If you have any questions relating to the CE accreditation of this activity, please contact AKH at jgoldman@akhcme.com.

If you have any questions relating to your certificate or have other issues with this activity, please contact myCME.Support@haymarketmedical.com.

Instructions

Default instructions: To obtain credit, a score of 70% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

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