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A New Chapter for BTK Inhibitors in B-cell Malignancies: Novel Options and Strategies for the Chronic Disease Model

A New Chapter for BTK Inhibitors in B-cell Malignancies: Novel Options and Strategies for the Chronic Disease Model

Format

Interactive Monograph

Time to Complete

1 hour

Released

September 13, 2018

Expires

August 28, 2019
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Maximum Credits

1.00 / ANCC Contact Hour

Accredited Provider



This activity is provided by Creative Educational Concepts.

Commercial Supporter

This activity is supported by an educational grant from AstraZeneca.

Program Description

The goal of this activity is to discuss the latest advances in BTK inhibitor therapy for B-cell malignancies, and to examine various strategies that nurses can utilize (e.g., shared decision making, motivational interviewing) to anticipate and manage adverse events.

Intended Audience

This activity is intended for oncology nurses and other healthcare professionals who manage cancer patients with B-cell malignancies.

Educational Objectives

Upon completion of this activity, participants will be able to:

  • Discuss the role of the B-cell receptor (BCR) pathway in the survival and proliferation of cancer cells
  • Evaluate clinical efficacy data for first- and second-generation BTK inhibitors in select B-cell malignancies (e.g., CLL/SLL, MCL) and explore the rationale for combination therapy with other antineoplastic agents
  • Assess potential toxicities that may arise with the use of BTK inhibitors and explore evidence-based strategies to ensure the timely recognition and proper management of these adverse events
  • Examine effective strategies that oncology nurses can employ to optimize therapy, anticipate and manage adverse events, improve adherence to oral chemotherapy, and promote collaborative discussion with other members of the oncology care team to ensure optimal patient outcomes

Conflict Of Interest Disclosure Policy

In accordance with the Food and Drug Administration, the authors have disclosed that there is the potential for discussions concerning off-label uses of a commercial product/device during this educational activity.

Any person who may contribute to the content of this continuing education activity must disclose relevant relationships (and any known relationships of their spouse/partner) with commercial interests whose products or services are discussed in educational presentations. A commercial interest is defined as an entity producing, marketing, re-selling, or distributing healthcare goods or services consumed by, or used on patients. Relevant relationships include receiving from a commercial interest research grants, consultant fees, travel, other benefits, or having a self-managed equity interest in a company.

Disclosure of a relationship is not intended to suggest or condone any bias in any presentation but is made to provide participants with information that might be of potential importance to their evaluation of a presentation.

Faculty

Amy Goodrich, RN, MSN, CRNP-AC
Research Associate
The Johns Hopkins School of Medicine
The Sidney Kimmel Cancer Center at Johns Hopkins
Baltimore, Maryland

Ms. Goodrich has no relevant financial relationships to disclose in relation to the content of this activity.

Jeannie Patrick, PharmD, BCOP
Clinical Oncology Pharmacist
Baptist Health Lexington
Lexington, Kentucky

Dr. Patrick has no relevant financial relationships to disclose in relation to the content of this activity.

Planners and Reviewers Disclosures

Planner:
Vanessa Carranza, PharmD
, has no relevant financial relationships to disclose in relation to the content of this activity.

Nurse Reviewer:
Sheila Hoff, RN
, discloses the following:
Speaker’s Bureau: Genentech, Inc.

Credit

1.00

Type

CNE Contact Hour(s)

Accreditation Statement

In support of improving patient care, Creative Educational Concepts is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Designation Statement

This activity is designated for 1.0 contact hours.

Learners are advised that accredited status does not imply endorsement by the provider or ANCC of any commercial products.

Disclosure of Unlabeled Use

This activity may include discussions of products or devices that are not currently approved for use by the Food and Drug Administration (FDA), or are currently investigational.

Disclaimer

It is the policy of CEC to ensure independence, balance, objectivity, scientific rigor, and integrity in their continuing education activities.

Those involved in the development of this continuing education activity have made all reasonable efforts to ensure that information contained herein is accurate in accordance with the latest available scientific knowledge at the time of accreditation of this continuing education activity. Information regarding drugs (e.g., their administration, dosages, contraindications, adverse reactions, interactions, special warnings, and precautions) and drug delivery systems is subject to change, however, and the learner is advised to check the manufacturer's package insert for information concerning recommended dosage and potential problems or cautions prior to prescribing, dispensing, or administering the drug or using the drug delivery systems.

Fair balance is achieved through ongoing and thorough review of all presentation materials produced by faculty, and all educational and advertising materials produced by supporting organizations, prior to educational offerings. Approval of credit for this continuing education activity does not imply endorsement by CEC for any product or manufacturer identified.

Instructions

To obtain credit, a score of 65% or better on the post-test is required. This activity is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test and evaluation, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME within your Profile/CME History, which you can access at any time.

If you have any questions relating to the accreditation of this activity, please contact Creative Educational Concepts at (866) 360-1717.

If you have any other questions relating to your certificate or other issues with this activity, please contact myCME.Support@haymarketmedical.com.

SYSTEM REQUIREMENTS

Hardware and Software Requirements
  • A computer with an internet connection
  • Internet Browser: Internet Explorer 7.x or higher, Firefox 4.x or higher, Safari 2.x or higher, or any other W3C standards compliant browser
  • Additional Software: Adobe Flash Player and/or an HTML 5 capable browser maybe required for video or audio playback. PowerPoint or Adobe Acrobat Reader may occasionally be required
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