Women who carry a BRCA gene mutation and opt for a preventive oophorectomy had an 80% reduction in the risk of ovarian, fallopian tube, or peritoneal cancer.
Researchers have developed a novel technique for detecting ALK rearrangements in non-small cell lung cancers that is more sensitive and easier to perform than currently available techniques.
Researchers report that a normal enzyme called SYK pairs with FLT3, the most commonly mutated enzyme found in acute myelogenous leukemia, to promote progression of the disease.
In research that could ultimately lead to many new medicines, scientists have developed a potentially general approach to design drugs from genome sequence. As a proof of principle, they identified a highly potent compound that causes cancer cells to attack themselves and die.
A new analysis confirmed the importance of known prognostic factors such as performance status and tumor grading for having a long-term outcome in patients treated with pazopanib for metastatic soft tissue sarcoma. In addition, hemoglobin at baseline was found to be a new prognostic factor.