Program Description:
For men with advanced prostate cancer, defined as prostate specific antigen (PSA) recurrence or metastatic disease, American Society of Clinical Oncology 2007 guidelines and National Comprehensive Cancer Network 2011 guidelines recommend luteinizing hormone-releasing hormone agonists or bilateral orchiectomy as first-line therapy. Timing of androgen deprivation therapy (ADT) administration in patients with advanced disease whose only evidence of cancer is a rising PSA may be influenced by PSA velocity, patient anxiety, and adverse events (AEs) associated with treatment. Intermittent ADT vs. continuous ADT may reduce AEs without affecting overall survival. Recent results from one large, phase 3 randomized trial suggest that treatment with intermittent ADT is noninferior to continuous ADT, with significantly better quality of life.
INTENDED AUDIENCE:
This activity has been designed to meet the educational needs of urologists, oncologists, and nurses involved in the treatment of patients with prostate cancer.
Activity Objectives:
After completing the activity, the participant should be better able to:
- Explain the role of androgen deprivation therapy (ADT) in the treatment of prostate cancer
- Describe selection criteria for appropriate candidates for ADT
- Evaluate the efficacy and safety of intermittent and continuous ADT for patients with prostate cancer
STATEMENT OF NEED:
Urologists, oncologists, and other clinicians who provide care for men with prostate cancer require balanced, evidence-based education focusing on the critical clinical nuances of ADT, including newer treatment protocols and how to optimize treatment success while minimizing or managing treatment-related adverse effects, to help them provide optimal, rational, and compassionate care to their patients with advanced prostate cancer.
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Credits
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Type
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Accreditation Statement
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Designation Statement
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1.00
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AMA PRA Category 1 Credit(s)TM
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This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Medical Education Resources (MER) and Haymarket Media, Inc. MER is accredited by the ACCME to provide continuing medical education for physicians.
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Medical Education Resources designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
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1.00
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CE for Nurses
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Medical Education Resources is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.
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This CE activity provides 1.00 contact hour of continuing nursing education.
Medical Education Resources is a provider of continuing nursing education by the California Board of Registered Nursing, Provider #CEP 12299, for 1.00 contact hour.
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Faculty:
Leonard G. Gomella, MD, FACS
Chairman, Department of Urology
Associate Director, Kimmel Cancer Center
Thomas Jefferson University in Philadelphia
Disclosures:
Disclosure of Conflicts of Interest
Medical Education Resources ensures balance, independence, objectivity, and scientific rigor in all our educational programs. In accordance with this policy, MER identifies conflicts of interest with its instructors, content managers, and other individuals who are in a position to control the content of an activity. Conflicts are resolved by MER to ensure all scientific research referred to, reported, or used in a CME activity conforms to the generally accepted standards of experimental design, data collection, and analysis. MER is committed to providing its learners with high-quality CME activities that promote improvements or quality in health care and not a commercial interest.
Faculty Disclosures
The faculty reported the following financial relationships with commercial interests whose products or services may be mentioned in this CME activity:
Leonard G. Gomella, MD, FACS
Grants/Research Support: Amgen, Centocor, Vivus.
Consulting Fees: Astellas, Bayer, Centocor, GSK, Ferring, Sanofi
Publishing Staff Disclosures
The content managers Debra A. Hughes and Mary Jo Krey of Haymarket Medical Education; Jody A. Charnow and Marina Galanakis of Haymarket Media, Inc.; and Julie Johnson, PharmD, of Medical Education Resources have disclosed that they have no relevant financial relationships or conflicts of interest relating directly or indirectly to this educational activity.
Disclosure of Unlabeled Use
This educational activity may contain discussion of approved and/or investigational uses of agents that are not indicated by the FDA. Medical Education Resources, Inc. (MER), and Haymarket Medical Education (HME) do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of MER and HME. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
The content and views presented in this educational activity are those of the authors and do not necessarily reflect those of Abbott Laboratories, Medical Education Resources or Haymarket Media, Inc. The authors have disclosed if there is any discussion of published and/or investigational uses of agents that are not indicated by the FDA in their presentations. The opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of Abbott Laboratories, Medical Education Resources, or Haymarket Media, Inc. Before prescribing any medicine, primary references and full prescribing information should be consulted. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. The information presented in this activity is not meant to serve as a guideline for patient management.
Accredited Provider:
This program is sponsored by Medical Education Resources, Inc., and produced by Haymarket Medical Education.
Commercial Supporter:
This activity is supported by an educational grant from Abbott Laboratories.
If you have any questions relating to the accreditation of this activity, please contact:
Medical Education Resources, Inc.
1500 West Canal Court
Littleton, CO 80120-5615
Tel: 1-800-421-3756
E-mail:
info@mer.org
Instructions:
To obtain credit, a post-test score of 70% or better is required. This CME is offered at no cost to participants. Please proceed with the activity until you have successfully completed this program, answered all test questions, completed the post-test survey, and have received a digital copy of your credit certificate. Your online certificate will be saved on myCME.com within your Profile/Exam History, which you can then access at any time.
To view the myCME privacy policy, please click here. To view the Medical Education Resources privacy policy, please click here.
SYSTEM REQUIREMENTS:
WINDOWS PC SYSTEM REQUIREMENTS:
266-MHz Pentium II; Windows 98 or higher; 64 MB RAM; 800 x 600 screen resolution
set for “High Color (16-Bit)”; Macromedia Flash Player 6 or higher.
MACINTOSH® SYSTEM REQUIREMENTS:
Power Mac g3 at 300 MHz; System 8.5 or higher (excluding Mac OSX); 96 MB RAM; 20
MB minimum hard disk space available; 800 x 600 screen resolution set to “Thousands
of Colors”; Macromedia Flash Player 6 or higher.