Zika Infects, Replicates in Immune Cells From Placenta

Share this content:
Zika Infects, Replicates in Immune Cells From Placenta
Zika Infects, Replicates in Immune Cells From Placenta

FRIDAY, May 27, 2016 (HealthDay News) -- New research, published online May 27 in Cell Host & Microbe, sheds light on how the Zika virus infects, but doesn't kill, placenta cells.

Scientists conducted experiments using immune cells from placentas of healthy women who had full-term babies delivered by cesarean section. The Zika virus used in the study is the strain circulating in Puerto Rico. The researchers said it's closely related to the strain in Brazil, where the virus-related birth defects became apparent last spring.

The researchers found that Zika can replicate in immune cells from the placenta without killing them. They said this may explain how the virus can pass through the placenta of a pregnant woman and infect developing brain cells in her fetus. When they examined placenta cells from different women, the researchers also found wide variation in the levels of Zika virus replication. This suggests some women may be more susceptible to infection than others.

"Not every pregnant woman who is infected by Zika transmits the virus to her fetus," senior author Mehul Suthar, Ph.D., an assistant professor of pediatrics at the Emory University School of Medicine in Atlanta, said in a university news release. "Host genetics and nonviral factors, including nutrition and microbiota, as well as timing may be influencing infectivity."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

U.S. Teens Not Getting Enough Moderate/Vigorous Exercise

U.S. Teens Not Getting Enough Moderate/Vigorous Exercise

And bad habits continue after high school for most

Cancer Patients Have Unrealistic Hopes Entering Clinical Trials

Cancer Patients Have Unrealistic Hopes Entering Clinical Trials

Study finding is a red flag, researcher says

Increased HIV Testing Among Men Who Have Sex With Men

Increased HIV Testing Among Men Who Have Sex ...

Data from 21 jurisdictions show higher percentages with negative HIV test 12 months before diagnosis

is free, fast, and customized just for you!

Already a member?

Sign In Now »