Zika Infects, Replicates in Immune Cells From Placenta

Share this content:
Zika Infects, Replicates in Immune Cells From Placenta
Zika Infects, Replicates in Immune Cells From Placenta

FRIDAY, May 27, 2016 (HealthDay News) -- New research, published online May 27 in Cell Host & Microbe, sheds light on how the Zika virus infects, but doesn't kill, placenta cells.

Scientists conducted experiments using immune cells from placentas of healthy women who had full-term babies delivered by cesarean section. The Zika virus used in the study is the strain circulating in Puerto Rico. The researchers said it's closely related to the strain in Brazil, where the virus-related birth defects became apparent last spring.

The researchers found that Zika can replicate in immune cells from the placenta without killing them. They said this may explain how the virus can pass through the placenta of a pregnant woman and infect developing brain cells in her fetus. When they examined placenta cells from different women, the researchers also found wide variation in the levels of Zika virus replication. This suggests some women may be more susceptible to infection than others.

"Not every pregnant woman who is infected by Zika transmits the virus to her fetus," senior author Mehul Suthar, Ph.D., an assistant professor of pediatrics at the Emory University School of Medicine in Atlanta, said in a university news release. "Host genetics and nonviral factors, including nutrition and microbiota, as well as timing may be influencing infectivity."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Multidrug-Resistant Bacteria Found in Hospital Sinks

Multidrug-Resistant Bacteria Found in Hospital Sinks

Drug-resistant bacteria can colonize in drains, spread to sinks, and eventually reach patients

AAP Addresses Rising Risks to Youth From New Marijuana Laws

AAP Addresses Rising Risks to Youth From New ...

Legalization in many states may lead parents, children to think the drug is benign

AAP Offers Guidance for Treating Victims of Sexual Assault

AAP Offers Guidance for Treating Victims of Sexual ...

Physicians need to be comfortable screening for it, offering additional help if needed

is free, fast, and customized just for you!

Already a member?

Sign In Now »