Zika Infects, Replicates in Immune Cells From Placenta

Share this content:
Zika Infects, Replicates in Immune Cells From Placenta
Zika Infects, Replicates in Immune Cells From Placenta

FRIDAY, May 27, 2016 (HealthDay News) -- New research, published online May 27 in Cell Host & Microbe, sheds light on how the Zika virus infects, but doesn't kill, placenta cells.

Scientists conducted experiments using immune cells from placentas of healthy women who had full-term babies delivered by cesarean section. The Zika virus used in the study is the strain circulating in Puerto Rico. The researchers said it's closely related to the strain in Brazil, where the virus-related birth defects became apparent last spring.

The researchers found that Zika can replicate in immune cells from the placenta without killing them. They said this may explain how the virus can pass through the placenta of a pregnant woman and infect developing brain cells in her fetus. When they examined placenta cells from different women, the researchers also found wide variation in the levels of Zika virus replication. This suggests some women may be more susceptible to infection than others.

"Not every pregnant woman who is infected by Zika transmits the virus to her fetus," senior author Mehul Suthar, Ph.D., an assistant professor of pediatrics at the Emory University School of Medicine in Atlanta, said in a university news release. "Host genetics and nonviral factors, including nutrition and microbiota, as well as timing may be influencing infectivity."

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Recent Decline in Prescription Opioid Use Among U.S. Teens

Recent Decline in Prescription Opioid Use Among U.S. ...

Lifetime prevalence of use peaked in 1989, 2002, and remained stable until decline in 2013 to 2015

Treatment Seeking Low Among Teens With Eating Disorders

Treatment Seeking Low Among Teens With Eating Disorders

Those with counter-stereotypic presentation even less likely to seek treatment

Optical Clearing Agent Ups No. of Laser Passes in Tattoo Removal

Optical Clearing Agent Ups No. of Laser Passes ...

Findings based on number of laser passes during a five-minute tattoo removal session

is free, fast, and customized just for you!

Already a member?

Sign In Now »