Worse LV Global Longitudinal Strain for STEMI With COPD

This article originally appeared here.
Share this content:
Worse LV Global Longitudinal Strain for STEMI With COPD
Worse LV Global Longitudinal Strain for STEMI With COPD

THURSDAY, Aug. 24, 2017 (HealthDay News) -- For patients with ST-segment elevation myocardial infarction (STEMI), those with chronic obstructive pulmonary disease (COPD) have significantly more impaired left ventricular (LV) global longitudinal strain (GLS), according to a study published in the Sept. 1 issue of The American Journal of Cardiology.

Laurien Goedemans, M.D., from the Leiden University Medical Center in the Netherlands, and colleagues used advanced two-dimensional speckle tracking echocardiography to compare STEMI patients with versus without COPD in terms of infarct size and LV systolic function. A total of 1,750 patients with STEMI were enrolled, of whom 7.6 percent had COPD. Left ventricular ejection fraction (LVEF) and wall motion score index were measured; biomarkers were used to assess infarct size. LV GLS was measured with two-dimensional speckle tracking.

The researchers found that based on peak levels of creatine kinase (1,315 versus 1,477 U/L; P = 0.106) and troponin T (3.3 versus 3.9 µg/L; P = 0.489), there were no differences in infarct size. Comparable LVEF (46 versus 47 percent; P = 0.591) and wall motion score index (1.38 versus 1.38; P = 0.690) were observed. Compared to patients without COPD, patients with COPD had significantly more impaired LV GLS (−13.9 ± 3.0 percent versus 14.7 ± 3.9 percent; P = 0.034).

"Patients with COPD exhibit more impaired LV GLS on advanced echocardiography than patients without COPD, suggesting a greater functional impairment at an early stage after STEMI," the authors write.

One author and the Department of Cardiology at the Leiden University Medical Center disclosed financial ties to the pharmaceutical and medical device industries.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!




Already a member?

Sign In Now »

Drug Lookup

Browse drugs by: BrandGenericDisease



Sign up for myCME e-newsletters




More in Home

Gender Difference in Survival Seen After Radical Cystectomy

Gender Difference in Survival Seen After Radical Cystectomy

Females have worse disease-free, cancer-specific, overall survival versus males with bladder cancer

Adult Obesity Prevalence Varies With Level of Urbanization

Adult Obesity Prevalence Varies With Level of Urbanization

Increased obesity for men, women living in medium, small versus large metropolitan statistical areas

Attitudes Among Obese Are Not Aligned With Healthy Living

Attitudes Among Obese Are Not Aligned With Healthy ...

Consumers with obesity report favoring taste and value rather than health and nutrition

is free, fast, and customized just for you!




Already a member?

Sign In Now »