Warfarin Persistence Higher Than Previously Reported in A-Fib

This article originally appeared here.
Share this content:
Warfarin Persistence Higher Than Previously Reported in A-Fib
Warfarin Persistence Higher Than Previously Reported in A-Fib

TUESDAY, Sept. 6, 2016 (HealthDay News) -- Among patients with atrial fibrillation (AF), the proportion of warfarin persistence is 0.91 at one year and 0.73 at four years, according to a study published online Aug. 27 in Cardiovascular Therapeutics.

Fredrik Björck, M.D., from Umeå University in Sweden, and colleagues examined warfarin persistence in AF patients. Data were included for 478 patients from the national quality register AuriculA for all AF patients in Sundsvall, Sweden.

The researchers found that after one year and four years, the proportion of warfarin persistence was 0.91 and 0.73, respectively. The risk of discontinuation was increased with previous intracranial bleeding, excessive alcohol use, anemia, and pulmonary or peripheral emboli (hazard ratios, 5.66, 2.54, 2.40, and 2.13, respectively). About half (50.5 percent) of discontinuations were due to questionable causes, including sinus rhythm, patient demand, and falls (33.9, 10.1, and 8.2 percent, respectively). Most treatment discontinuers were changed to aspirin (43.1 percent), and many were left without medical stroke prophylaxis (40.4 percent).

"Although persistence to warfarin among AF patients proves higher than previously reported, there is room for improvement since half of the discontinuers have questionable reasons for treatment stop and the majority of them receive no other efficient stroke prophylaxis," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease


More in Home

Dermatography Helps Lessen Appearance of Surgical Scars

Dermatography Helps Lessen Appearance of Surgical Scars

Pigments can restore more natural skin appearance that patients are happy with

Drug-Resistant Bacteria Live in America's Water Systems

Drug-Resistant Bacteria Live in America's Water Systems

Bacteria found in plumbing may sicken thousands each year

Deep Brain Stimulation May Improve TBI Symptoms

Deep Brain Stimulation May Improve TBI Symptoms

Deep brain stimulation appears to boost function and quality of life

is free, fast, and customized just for you!

Already a member?

Sign In Now »