Waiting 10 Months for Colonoscopy May Raise CRC Risk

Share this content:
Waiting 10 Months for Colonoscopy May Raise CRC Risk
Waiting 10 Months for Colonoscopy May Raise CRC Risk

TUESDAY, April 25, 2017 (HealthDay News) -- Follow-up colonoscopy after 10 months is associated with an increased risk of colorectal cancer and advanced-stage disease among patients with a positive fecal immunochemical test (FIT) result, according to a study published online April 25 in the Journal of the American Medical Association.

Douglas A. Corley, M.D., Ph.D., from Kaiser Permanente Northern California in Oakland, and colleagues examined the time to colonoscopy after a positive FIT result and its correlation with the risk of colorectal cancer for 70,124 patients aged 50 to 70.

The researchers found that there were 2,191 cases of any colorectal cancer and 601 cases of advanced-stage disease. There were no significant differences between follow-up at two months (24,644 participants), three months (8,666 participants), four to six months (5,251 participants), or seven to nine months (1,335 participants) compared with follow-up within eight to 30 days (27,176 participants) for the risk of any colorectal cancers (cases per 1,000 patients: 28, 31, 31, 43, and 30, respectively) or advanced-stage disease (cases per 1,000 patients: seven, seven, nine, 13, and eight, respectively). For examinations at 10 to 12 months (748 participants) or at more than 12 months (747 participants), risks were significantly higher for any colorectal cancer (odds ratios, 1.48 and 2.25) and advanced-stage disease (odds ratios, 1.97 and 3.22).

"Further research is needed to assess whether this relationship is causal," the authors write.

One author disclosed ties to Wyeth/Pfizer.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

NTproBNP Levels Are Significantly Lower in Blacks

NTproBNP Levels Are Significantly Lower in Blacks

Higher NTproBNP levels linked to increased risk of death; this association did not differ by race

Data May Weigh on Pros/Cons of Expanded Care Optometry

Data May Weigh on Pros/Cons of Expanded Care ...

Majority of residents in Kentucky, Oklahoma, New Mexico live within 30 minutes of ophthalmologist

Gaps Seen Between Hearing Loss, Receipt of Medical Evaluation, Tx

Gaps Seen Between Hearing Loss, Receipt of Medical ...

About 20.6 percent of those with hearing less than excellent/good had visited doctor for hearing issues

is free, fast, and customized just for you!

Already a member?

Sign In Now »