Vonoprazan-Based Triple Tx Feasible for H. pylori

This article originally appeared here.
Share this content:
Vonoprazan-Based Triple Tx Feasible for <i>H. pylori</i>
Vonoprazan-Based Triple Tx Feasible for H. pylori

THURSDAY, Aug. 25, 2016 (HealthDay News) -- The potassium-competitive acid blocker vonoprazan-based triple therapy seems safe and effective compared with conventional proton pump inhibitor (PPI)-based triple therapy as first-line treatment against Helicobacter pylori, according to a study published online Aug. 17 in the Journal of Digestive Diseases.

Satoki Shichijo, M.D., Ph.D., from the University of Tokyo, and colleagues performed a multicenter study involving 2,715 patients who received first-line H. pylori eradication therapy. Vonoprazan-based triple therapy was compared with conventional PPI-based triple therapy.

The researchers found that eradication rates were 87.2 and 72.4 percent for vonoprazan-based and conventional PPI-based therapy, respectively (P < 0.01). There were 10 cases of diarrhea, six of nausea/vomiting, and five of rash in the vonoprazan-based therapy group; these rates were not higher than those in the conventional PPI-based group.

"Vonoprazan-based triple therapy is feasible; it showed a higher eradication rate than conventional PPIs as a first-line regimen," the authors write.

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

Physician Excess Charges Create Financial Burden for Patients

Physician Excess Charges Create Financial Burden for Patients

Fees affect uninsured Americans, privately insured patients who use out-of-network physicians

Current Guidelines for Pediatric Tonsillectomies Questioned

Current Guidelines for Pediatric Tonsillectomies Questioned

Understanding of longer-term outcomes or effects in subpopulations deemed lacking

Acupuncture Reduces Crying in Infants With Colic

Acupuncture Reduces Crying in Infants With Colic

No serious adverse events reported in study of colicky infants

is free, fast, and customized just for you!

Already a member?

Sign In Now »